CAZyme Information: MGYG000000644_00609

Basic Information

• Species: Prevotella sp900546535
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900546535
• CAZyme ID: MGYG000000644_00609
• CAZy Family: GH84
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
845	MGYG000000644_9|CGC2	95521.66	7.5728

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000644	3556677	MAG	Madagascar	Africa

• Gene Location: Start: 62844; End: 65381 Strand: +

Full Sequence      

MTRKMLMAALLMAAFAQGTQAQDLSGQRSEKQDVNMIPGKKLDHHGLIVSPTPHLLNVDA
ANRLDLQKGVKVIDKKGKFADDVKFLTANAKGIRLTIDFGEKLAAKAGVKPVSGAYSLKA
DAKGIQIVGYDERGAFYGLQTLRQIVNSEMAKGQMPYTTCNDYPDLPNRGVVEGFYGEPW
SHQVRLSLIDYYGKNKMNTYLYGPKDDPYHSCPNWRLPYPEKEAKNISELVQACRRNRVD
FVWAIHPGQDIKWNEEDYQNLVHKLDLMYDLGVRSFAIFFDDISGEGANPVKQSELLNRL
AKEFVKAKGDVTPLVMCPTDYTRLWANPKPTGSLAIFGNTLDPSINVFWTGDVVCSDLTR
ETLDWVNSRIKRPAYYWWNFPVTDYARHIIMQGPTYGLQTDLTNKDLCGFVSNPMEHGEA
SKLALYGVADYSWNIANYNPLDNWERGLVDLTPEAHEAYRTFAMHSCDTETGYRRIESWE
TKSFRIDNFTDAQFNALQNEFVKVKNAPAQMEANCKNALLMKELRPWLTEFGKLGERGLK
TMSLIKEYKAGNDQAFWEGYVNNRMSKEDVAAYEKHKSGTMVLQPFYEQSMDDMASGFFK
KLTGKVPAFYKGIGTYATLRTTQSKAMFDNDSTTYYTSGNGQNTGDWIGADLGCVRSVSE
VRILQGRNSVDDVDYFDNTVLEYSVDRKEWKALTGELKKQYIINWKTDTPVEARYIRIKK
LKSDKRNWAAVRTFEVNPTTPERLSFPVEATNLQAAMYGFDENPCTSFTNEGILTMGVEK
EVKGYTLLLKLTPGSSLVCRQLNAKGKVLATTTIDSSFCKVELVKKAAKLQIEGSAEIFE
IIPEK

Enzyme Prediction     

No EC number prediction in MGYG000000644_00609.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH84	169	463	3.3e-106	0.9932203389830508

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07555	NAGidase	2.22e-166	169	462	1	293	beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838	Glyco_hydro_20b	1.33e-11	51	162	6	123	Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
pfam00754	F5_F8_type_C	3.91e-09	626	732	16	124	F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
cd00057	FA58C	2.24e-06	628	736	29	141	Substituted updates: Jan 31, 2002
COG3525	Chb	0.004	113	223	205	316	N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BCI62100.1	0.0	23	844	31	854
ALB75783.1	0.0	23	842	30	850
AHF11939.1	0.0	23	845	29	855
ADV43394.1	0.0	23	842	28	847
BBL05673.1	0.0	5	842	8	844

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2J4G_A	8.69e-153	116	608	80	585	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482],2J4G_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with n-butyl- thiazoline inhibitor [Bacteroides thetaiotaomicron VPI-5482]
5MI4_A	8.82e-153	116	608	92	597	BtGH84mutant with covalent modification by MA3 [Bacteroides thetaiotaomicron VPI-5482],5MI5_A BtGH84 mutant with covalent modification by MA3 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482],5MI6_A BtGH84 mutant with covalent modification by MA3 in complex with Thiamet G [Bacteroides thetaiotaomicron VPI-5482],5MI7_A BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc [Bacteroides thetaiotaomicron VPI-5482]
2JIW_A	8.95e-153	116	608	81	586	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with 2- Acetylamino-2-deoxy-1-epivalienamine [Bacteroides thetaiotaomicron VPI-5482],2JIW_B Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with 2- Acetylamino-2-deoxy-1-epivalienamine [Bacteroides thetaiotaomicron VPI-5482]
2CHO_A	8.95e-153	116	608	81	586	Bacteroidesthetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482],2CHO_B Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity [Bacteroides thetaiotaomicron VPI-5482]
2J47_A	8.95e-153	116	608	81	586	Bacteroidesthetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor [Bacteroides thetaiotaomicron VPI-5482],2W4X_A BtGH84 in complex with STZ [Bacteroides thetaiotaomicron VPI-5482],2W66_A BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W66_B BtGH84 in complex with HQ602 [Bacteroides thetaiotaomicron VPI-5482],2W67_A BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2W67_B BtGH84 in complex with FMA34 [Bacteroides thetaiotaomicron VPI-5482],2WCA_A BtGH84 in complex with n-butyl pugnac [Bacteroides thetaiotaomicron VPI-5482],2XJ7_A BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XJ7_B BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine [Bacteroides thetaiotaomicron VPI-5482],2XM1_A BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM1_B BtGH84 in complex with N-acetyl gluconolactam [Bacteroides thetaiotaomicron VPI-5482],2XM2_A BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],2XM2_B BtGH84 in complex with LOGNAc [Bacteroides thetaiotaomicron VPI-5482],4UR9_A Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],4UR9_B Structure of ligand bound glycosylhydrolase [Bacteroides thetaiotaomicron],5FKY_A Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FKY_B Structure of a hydrolase bound with an inhibitor [Bacteroides thetaiotaomicron],5FL0_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL0_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_A Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron],5FL1_B Structure of a hydrolase with an inhibitor [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q89ZI2	9.14e-152	116	608	102	607	O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q0TR53	1.76e-91	116	545	133	572	O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q8XL08	1.22e-90	116	545	133	572	O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
P26831	1.33e-50	125	737	143	795	Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
O60502	5.06e-36	170	439	63	337	Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000259	0.998969	0.000238	0.000192	0.000170	0.000143

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000644_00609.