CAZyme Information: MGYG000000666_02392

Basic Information

• Lineage: Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; UBA1829
• CAZyme ID: MGYG000000666_02392
• CAZy Family: GH39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1148	MGYG000000666_158|CGC1	129355.06	9.6719

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000666	4523435	MAG	Kazakhstan	Asia

• Gene Location: Start: 795; End: 4241 Strand: -

Full Sequence      

MKKFLYGFLLFPLLLPASEVAGSMNLDAFTAPRAYVHNGEKVHQTLRHSTNGPEGRPATC
LTWDSSKKNYAELNLRNAPLIPGRSAAEVELDYYSDGSGQVNTFGFRMFDAKNECFQWIV
PAHDNTPGWKTVRATLSPDAFTDSWGKQKTGKIEPPLRLIGFAVGYAPDTSGPVWFGKMA
WRIPEKRPGIPALTHNWTFDSNAERWNSWGISHMNRKQIRAEKRGNIYLNERMFSLRPIS
EPEAIQLNGTLESGEAEVCLTLFDGTGKQRTLPPQRFSRKNNAIRWDIRAIHPPLKLSLL
RFRTLADNTSLRLRSLEVWERRAPERAVDVALDTGHPLHLVLPGKEQKAVLRLENRTKQP
LRLESEFEVADFFGKVDSFSRTLEFAPRQTHSISLPVDTYPRDGIFMVQYTFRAPGSTES
FHGERTYARMVPAGPTAKIDTADKRNFLFGICTHSERWSRRDRELEALAAAFSGAKIIRN
SVGWGEIQPRKEIWNYEMFDELVSLYGKYGIELQGGFGLCAGWGKAHDAKLRNGKPDPMN
NGRSMPELGAWTEYVRRTVARYRDQIRYWEVWNEPDLTHFANFGVEDYLRLQKASYSAAR
EASPSAIVMNGGFAGLGNAPQIQYQRTFLECGKGSFDLHAFHQHGNFRSFRKIIDNVFLP
LRKETGTERIPWYANETAMHSLGGQDRAQAETLFKKLIHSWARGAVGYTWYDLRNDGFSA
TDAEHNYGMMTNDFYPKAVYPAYAALVGLYRGMEFLRQLQPAPGEYLYLFRARHGRELAA
ATWREPVEAAFSGMLFAGVTDGTSLEIADLMGNRRPLPLRNGRFLHQSARIPETLLLHQA
TRLSFVPILRTKAEGPAAEGYTVRVQAELDNPFDSELAMKLTLNAPIPFRVSGGTERLLK
AAPGKKAAAEYLLQTGKTEENGFRPYRLAFRVETADGSVAELGLPVHPAKRLSSKGIGGK
VDFLLNHRTQVVSLYDKVPGRSIWQGAEDLSAEVRCGLNKKALLVTAIVQDDIHLPQGRG
KLLWQGDSIQLFLELPGRGTWVAGGSLNESGKAEKWIWNAPKGCSAEDALAAMGFHAERK
DKKTIYHFQIPRREFQLTESLLNHGFRFNLLVNDADTKRDGREGWIRIAPGAGDEVAPIH
YPIVFFSR

Enzyme Prediction     

No EC number prediction in MGYG000000666_02392.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH39	491	786	2.5e-26	0.728538283062645

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd09621	CBM9_like_5	4.27e-48	962	1146	2	188	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other functional domains such as glycosyl hydrolases. The CBM9 module in these architectures may be involved in binding to carbohydrates.
cd00241	DOMON_like	3.49e-07	975	1122	3	154	Domon-like ligand-binding domains. DOMON-like domains can be found in all three kindgoms of life and are a diverse group of ligand binding domains that have been shown to interact with sugars and hemes. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.
pfam01229	Glyco_hydro_39	1.96e-05	550	649	126	234	Glycosyl hydrolases family 39.
pfam00331	Glyco_hydro_10	1.58e-04	440	607	3	164	Glycosyl hydrolase family 10.
COG3693	XynA	0.001	480	607	65	188	Endo-1,4-beta-xylanase, GH35 family [Carbohydrate transport and metabolism].

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AVM47149.1	7.90e-181	61	1147	216	1307
AVM46276.1	2.84e-173	63	1147	49	1137
AVM44759.1	1.12e-152	226	1147	59	965
AHF94342.1	2.07e-135	328	1148	215	1034
AHF90198.1	4.22e-133	36	1146	35	1005

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5JVK_A	3.15e-18	443	839	100	500	Structuralinsights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. [Bacteroides cellulosilyticus],5JVK_B Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. [Bacteroides cellulosilyticus],5JVK_C Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2. [Bacteroides cellulosilyticus]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000296	0.999063	0.000165	0.000153	0.000139	0.000140

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000666_02392.