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CAZyme Information: MGYG000000675_03442
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides congonensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides congonensis | |||||||||||
| CAZyme ID | MGYG000000675_03442 | |||||||||||
| CAZy Family | GH97 | |||||||||||
| CAZyme Description | Retaining alpha-galactosidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 15000; End: 16949 Strand: - | |||||||||||
Full Sequence Download help
| MKINYILFLL TAAFCYPSIT VAKIIETSSP DKKNVITIET DNQVSYSLSR NGTKILDTCP | 60 |
| LSLTVGNDTW GTDKCRKVTR KSVSEKVEFI VPRKYKEAVD NYNQIELIYK DYKIEFRVYN | 120 |
| DGVAYRFVST ANNKQPVKKE SVSYCFEQDH TSYTLLTDQL QNWFEQDYTV KPINALPKDS | 180 |
| FSVAPVMVEV DKYKVLLAEA NLYNYPGMYL QPAKESFHGI FANYPDKEVP YEGDNKIYVS | 240 |
| TRKDYLIPNC GKRVFPWRVT GIFDNASSIL QSELIYLLSE EKEQAADYTW VKPGKVLWDW | 300 |
| WNDRNIYHIN FKSGINTDTY LYLVDYAAKH HIEYVLIDEG WSARNDLLTL NPDVNIPHIC | 360 |
| KYAAEKEVGI QLWSKWVNIM RQMDEAFAQF SKWGVKGVKI DFMDRNDAKM VNFYEQVAVK | 420 |
| ATQYKLLVDF HGSYPNEGMR RKYPNLMTRE GVIGLEYNKW SKRATVTHDV IIPYLRMWVG | 480 |
| PMDYTPGAML NAHPETFYEN QHEPMSQGTR SHQIAMYVVY ESPLQMISDS PTKYDENLRS | 540 |
| FEFIKSIPTT WDETVPLEGE VGEYIALARR HGNTWYIGVI NGSTPRSLEF DLSFIGKGKK | 600 |
| NIKAHYDGVN ADQQAKDSQL IQYTLPENSN KLSINLCRGG GYIGIINIE | 649 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH97 | 16 | 643 | 2.7e-187 | 0.9857369255150554 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam10566 | Glyco_hydro_97 | 8.57e-123 | 287 | 548 | 1 | 278 | Glycoside hydrolase 97. This domain is the catalytic region of the bacterial glycosyl-hydrolase family 97. This central part of the GH97 family protein sequences represents a typical and complete (beta/alpha)8-barrel or catalytic TIM-barrel type domain. The N- and C-terminal parts of the sequences, mainly consisting of beta-strands, form two additional non-catalytic domains. In all known glycosidases with the (beta-alpha)8-barrel fold, the amino acid residues at the active site are located on the C-termini of the beta-strands. |
| pfam14508 | GH97_N | 2.25e-52 | 29 | 280 | 1 | 234 | Glycosyl-hydrolase 97 N-terminal. This N-terminal domain of glycosyl-hydrolase-97 contributes part of the active site pocket. It is also important for contact with the catalytic and C-terminal domains of the whole. |
| pfam14509 | GH97_C | 4.13e-28 | 551 | 636 | 1 | 86 | Glycosyl-hydrolase 97 C-terminal, oligomerization. Glycosyl-hydrolase-97 is made up of three tightly linked and highly conserved globular domains. The C-terminal domain is found to be necessary for oligomerization of the whole molecule in order to create the active-site pocket and the Ca++-binding site. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QIU93149.1 | 0.0 | 1 | 649 | 1 | 648 |
| ASM64931.1 | 0.0 | 1 | 649 | 1 | 648 |
| QRP59557.1 | 0.0 | 1 | 649 | 1 | 648 |
| QQT78558.1 | 0.0 | 1 | 649 | 1 | 648 |
| QUU06532.1 | 0.0 | 4 | 649 | 2 | 646 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3A24_A | 2.80e-145 | 29 | 642 | 6 | 636 | Crystalstructure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron],3A24_B Crystal structure of BT1871 retaining glycosidase [Bacteroides thetaiotaomicron] |
| 5E1Q_A | 4.77e-144 | 29 | 642 | 20 | 650 | Mutant(D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482],5E1Q_B Mutant (D415G) GH97 alpha-galactosidase in complex with Gal-Lac [Bacteroides thetaiotaomicron VPI-5482] |
| 5HQ4_A | 2.21e-58 | 98 | 641 | 76 | 653 | AGlycoside Hydrolase Family 97 enzyme from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8],5HQA_A A Glycoside Hydrolase Family 97 enzyme in complex with Acarbose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQC_A | 2.21e-58 | 98 | 641 | 76 | 653 | AGlycoside Hydrolase Family 97 enzyme R171K variant from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
| 5HQB_A | 5.77e-58 | 98 | 641 | 76 | 653 | AGlycoside Hydrolase Family 97 enzyme (E480Q) in complex with Panose from Pseudoalteromonas sp. strain K8 [Pseudoalteromonas sp. K8] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8A6L0 | 1.64e-146 | 8 | 642 | 6 | 657 | Retaining alpha-galactosidase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_1871 PE=1 SV=1 |
| G8JZS4 | 6.12e-57 | 96 | 642 | 118 | 719 | Glucan 1,4-alpha-glucosidase SusB OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=susB PE=1 SV=1 |
| D7CFN7 | 2.11e-50 | 40 | 645 | 55 | 619 | Probable retaining alpha-galactosidase OS=Streptomyces bingchenggensis (strain BCW-1) OX=749414 GN=SBI_01652 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000306 | 0.999072 | 0.000196 | 0.000156 | 0.000137 | 0.000133 |