CAZyme Information: MGYG000000692_00524

Basic Information

• Species: Prevotellamassilia sp900543155
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotellamassilia; Prevotellamassilia sp900543155
• CAZyme ID: MGYG000000692_00524
• CAZy Family: GH84
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1151		125668.46	5.4589

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000692	2730358	MAG	Kazakhstan	Asia

• Gene Location: Start: 9999; End: 13454 Strand: -

Full Sequence      

MNKKSFLIGVAALMLPMAMHAQYTIYPVPHEQTAGTGKVSFTKTVNVICDNGIDQYTKKR
VTNVFAEKGITVNFSDAASTTESNVYLGINGANGKGNEVATSLGLALDVLSKEGKFDRHI
LSLTDAGNGVAQLLVLGENTDATFMGLASLEQILDNGTSDLQTVTLNDYADLKERGIIEG
FYGKPYSSEVRKDLLRFMMRNKMNCYVYGPKSDPYHSGKWSEPYPTTLTESQKTSGFVDQ
QALKDFTDVSHETKVSVVWAIHPGNSLLNDDNVVSKIMGKFENMYNLGFRQFAVFCDDVG
VPSTQEGMDKTAQRVTDIQRSIESKWNIAGADPADTVKALRFTPQIYCRGFAGSDSQFNG
FFQALSKLPANVTVYYTGGGVWSVPNNGDLNTVQNQFGRNVIWWWNYPCNDNGTGPNEIY
PLDMKSNFYDMPNVVSGSTIESELTASNQGILCNPMEQGSASRTPVFSAGDYSWNNKGFD
NLKSWEASFKSLFPGNEKLQKAYRFLAPYLSKNDPESLNKIISNYKSTKDGAELGALMDE
IISNCEVMNGTEHSSVVSDSLLYVDIKPWVLRLQAMAQTVKQLVNLKNVDEIEQAWADYR
AGVSKANTLSTADEFMARHMSGFGSDGISTEPRLTHASYRYLTPFVDYLKQNALNGRFGN
ENTDCKPFTNVEVSNLTVKKISDKYSVKGTATLPNGGYAGIELPSPMLISAITIPASVVS
AATDCKFLYSADGKDWKRATEAKTLVNDYVRYLVVLNESGAEKEFSFGTGIRLVVNSVDV
KTATAPTDAEFWSGHTANLLADGNYGTYVCLNRVQKANDTYSVELAEPEVIRNVRIVMGT
TNGDYPTKGTVTVSADGKKWTQLTVSGSKDLAFRMDAPQIKKVGTDSDSGADIMALDFMP
PLVNGKFTPIEAKYVKFRVSVANTEKWLRLHEIEVNGNAVATKAPIEATNGVVIWDSSDN
NPLTSSANYTLGTAKGGEFVYNINSAFDVEQLTFFCDETTLTGVKYAVTTDGKTWTDVEA
AQANGVVKFNFEKDNHIKALRITWNSATVPAIYEVSEKVNAETSMPVISRIGAVQAEAAE
GAVSVSVKGNHLVAESATGLRAVNVYTLDGRHVLSQSLAGAHQASLPIVDAAVIVKVTLT
NGTMRSYKLTK

Enzyme Prediction     

No EC number prediction in MGYG000000692_00524.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH84	175	505	4e-67	0.9864406779661017

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07555	NAGidase	3.32e-110	175	506	1	293	beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam02838	Glyco_hydro_20b	4.29e-09	22	156	1	110	Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
pfam00754	F5_F8_type_C	1.02e-04	790	933	7	127	F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QFQ11845.1	1.25e-231	3	1148	4	1132
QUT77745.1	1.14e-106	13	1055	10	1016
BCI64753.1	4.31e-100	10	1055	9	1019
AHF13697.1	2.37e-97	23	1138	25	1102
AHF13792.1	6.17e-91	23	1026	9	997

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6PWI_A	7.48e-67	22	585	33	565	Structureof CpGH84D [Clostridium perfringens ATCC 13124],6PWI_B Structure of CpGH84D [Clostridium perfringens ATCC 13124]
6PV4_A	1.11e-54	23	652	32	643	Structureof CpGH84A [Clostridium perfringens ATCC 13124],6PV4_B Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_C Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_D Structure of CpGH84A [Clostridium perfringens ATCC 13124]
6PV5_A	1.52e-51	24	609	41	600	Structureof CpGH84B [Clostridium perfringens ATCC 13124]
2CBI_A	6.62e-45	27	541	18	478	Structureof the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBI_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBJ_A Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2CBJ_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2V5C_A Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2V5C_B Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2VUR_A Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2VUR_B Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2X0Y_A Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens],2X0Y_B Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens]
5OXD_A	8.38e-45	27	541	20	480	Complexof a C. perfringens O-GlcNAcase with a fragment hit [Clostridium perfringens]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P26831	3.06e-60	23	935	39	943	Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
Q89ZI2	2.00e-43	132	494	110	433	O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
Q8XL08	5.08e-43	27	541	48	508	O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Q0TR53	8.86e-43	27	541	48	508	O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
O60502	1.42e-11	176	476	63	335	Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000234	0.999157	0.000160	0.000166	0.000148	0.000138

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000692_00524.