You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000715_01207
You are here: Home > Sequence: MGYG000000715_01207
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-110 sp900544705 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; CAG-110; CAG-110 sp900544705 | |||||||||||
| CAZyme ID | MGYG000000715_01207 | |||||||||||
| CAZy Family | CBM50 | |||||||||||
| CAZyme Description | Trifunctional nucleotide phosphoesterase protein YfkN | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 40637; End: 44176 Strand: - | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK09419 | PRK09419 | 2.88e-165 | 12 | 1119 | 17 | 1135 | multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase/5'-nucleotidase. |
| COG0737 | UshA | 2.12e-84 | 626 | 1123 | 29 | 507 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family [Nucleotide transport and metabolism, Defense mechanisms]. |
| PRK09558 | ushA | 2.67e-71 | 621 | 1132 | 29 | 548 | bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed |
| COG0737 | UshA | 5.28e-70 | 45 | 556 | 20 | 509 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family [Nucleotide transport and metabolism, Defense mechanisms]. |
| cd00845 | MPP_UshA_N_like | 3.59e-59 | 626 | 863 | 3 | 247 | Escherichia coli UshA-like family, N-terminal metallophosphatase domain. This family includes the bacterial enzyme UshA, and related enzymes including SoxB, CpdB, YhcR, and CD73. All members have a similar domain architecture which includes an N-terminal metallophosphatase domain and a C-terminal nucleotidase domain. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| VDN48620.1 | 1.06e-121 | 43 | 1118 | 81 | 1119 |
| QUI23903.1 | 3.41e-121 | 44 | 1114 | 77 | 1111 |
| BCJ95849.1 | 2.76e-83 | 619 | 1141 | 36 | 515 |
| QGU94268.1 | 6.22e-81 | 1 | 1125 | 7 | 1078 |
| QUH21387.1 | 2.10e-79 | 623 | 1114 | 38 | 495 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2Z1A_A | 5.82e-53 | 626 | 1143 | 32 | 539 | Crystalstructure of 5'-nucleotidase precursor from Thermus thermophilus HB8 [Thermus thermophilus HB8] |
| 3IVD_A | 7.77e-41 | 626 | 1101 | 9 | 469 | Putative5'-Nucleotidase (c4898) from Escherichia Coli in complex with Uridine [Escherichia coli O6],3IVD_B Putative 5'-Nucleotidase (c4898) from Escherichia Coli in complex with Uridine [Escherichia coli O6],3IVE_A Putative 5'-Nucleotidase (c4898) from Escherichia Coli in complex with Cytidine [Escherichia coli O6] |
| 7D0V_A | 6.46e-40 | 623 | 1101 | 4 | 497 | ChainA, Snake venom 5'-nucleotidase [Naja atra],7D0V_B Chain B, Snake venom 5'-nucleotidase [Naja atra] |
| 5H7W_A | 2.08e-39 | 626 | 1101 | 7 | 497 | Crystalstructure of 5'-nucleotidase from venom of Naja atra [Naja atra],5H7W_B Crystal structure of 5'-nucleotidase from venom of Naja atra [Naja atra] |
| 7JV9_A | 2.97e-37 | 626 | 1114 | 7 | 510 | HumanCD73 (ecto 5'-nucleotidase) in complex with compound 12 [Homo sapiens],7JV9_B Human CD73 (ecto 5'-nucleotidase) in complex with compound 12 [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| O34313 | 2.00e-95 | 38 | 1132 | 31 | 1174 | Trifunctional nucleotide phosphoesterase protein YfkN OS=Bacillus subtilis (strain 168) OX=224308 GN=yfkN PE=1 SV=1 |
| A9BJC1 | 6.68e-44 | 626 | 1112 | 26 | 481 | Mannosylglucosyl-3-phosphoglycerate phosphatase OS=Petrotoga mobilis (strain DSM 10674 / SJ95) OX=403833 GN=mggB PE=1 SV=1 |
| P26265 | 1.09e-42 | 49 | 619 | 21 | 601 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=cpdB PE=3 SV=2 |
| P29240 | 1.44e-41 | 626 | 1132 | 34 | 546 | 5'-nucleotidase OS=Diplobatis ommata OX=1870830 PE=2 SV=1 |
| P08331 | 2.75e-40 | 49 | 547 | 21 | 549 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase OS=Escherichia coli (strain K12) OX=83333 GN=cpdB PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000402 | 0.998639 | 0.000372 | 0.000200 | 0.000191 | 0.000173 |
