CAZyme Information: MGYG000000720_02959

Basic Information

• Lineage: Bacteria; Verrucomicrobiota; Lentisphaeria; Victivallales; Victivallaceae; Victivallis
• CAZyme ID: MGYG000000720_02959
• CAZy Family: GH39
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
998		110523.17	9.1888

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000720	3759035	MAG	Kazakhstan	Asia

• Gene Location: Start: 3171; End: 6167 Strand: -

Full Sequence      

MRLLLLFMLTVLALVLRGGEIFDFARLSDRIELVHYQKGSAAKVGKIDGRDALELFFDPA
RNSWNTIAIKNYQRPRLPLFRKCRIALEVWLPRNHAVRSVNLELCDSTGEMLQYPGVVSA
QDHGWRKVAWEIDTASRAPHSWGGKKKNGVPDGKTMIRNFSCSFRSGGAAGSLAFGKVFL
EVEEAPLEFGVATGNGFPVITRGREAEFGILLKNGNPVVRRGKAKWEISTANGDKLSAGG
DDWEVAPRSEKVIPLPAPAAYGLYNLRVNIDGEQERKFRFGYMAPAGPVDGPIRGFVLGV
CEHPESLSDEEAEVWTRAAALCGARVIRGAGSWNGIEWRKGYPDYHVEDTMVERLERYHM
KMSLLLLGTPGWAVAKDWKPLMPGKKYWPMPDLDAWRKYVRTLASRWGDRLYSLEVWNEP
DLRTNGNFTSREYFKMLKAANDAAKSVNPGLQIQSGGLAGIDLPASISADPRYAWKLLKD
EAANYDVFALHNHQVYLGYEDMVGRFLKYRREARTGKPWYANETAITSSTVGDEKQAHTL
FQKIIYTMSLMNRGAIGYNWYNLVEKTKYPAGHPERHFGLLTPELEPKAAYLAYNTVAGH
FREAVPEREFSGPGDSFRLYCFKAANGDYLVPGWSVSDKGNKAILLSGITGRAVRVDLNG
NLEPLAATNGGVLFTLSETPAFIRISGQKKAPLCMGAPLELPDTLILRGGEMTTLKAVLR
NSGPKAVSLNVVADAPRGVLVRPRSIREPLAAGASRQVEFSVRAQDSFESGNLRFQVNPG
MGVVSVRLERAVRLGDAPGLKHDLFLGERSQLVSMYPSAAETTHLQWQGAADLSGKFFLS
ARNQVLTIRCDVTDDRHRQRFSGSEIWQNDSLQIALTLPGQNTFWELGAALTDSGKAVGY
CWRAPAGFRAEQAIEKIGVEVTRDEARKLTRYILKIPFDAVGLTGEKLGAGIRFNALIND
CDETATRESYLRLAPGLGDGAASPELSVLIYQQEAEQK

Enzyme Prediction     

No EC number prediction in MGYG000000720_02959.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH39	347	614	1.3e-21	0.6635730858468677

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd09621	CBM9_like_5	2.90e-63	802	991	1	188	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other functional domains such as glycosyl hydrolases. The CBM9 module in these architectures may be involved in binding to carbohydrates.
cd09619	CBM9_like_4	2.34e-10	827	986	30	185	DOMON-like type 9 carbohydrate binding module. Family 9 carbohydrate-binding modules (CBM9) play a role in the microbial degradation of cellulose and hemicellulose (materials found in plants). The domain has previously been called cellulose-binding domain. The polysaccharide binding sites of CBMs with available 3D structure have been found to be either flat surfaces with interactions formed by predominantly aromatic residues (tryptophan and tyrosine), or extended shallow grooves. CBM9 domains found in this uncharacterized heterogeneous subfamily are often located at the C-terminus of longer proteins and may co-occur with various other domains.
cd00241	DOMON_like	9.15e-08	827	960	12	146	Domon-like ligand-binding domains. DOMON-like domains can be found in all three kindgoms of life and are a diverse group of ligand binding domains that have been shown to interact with sugars and hemes. DOMON domains were initially thought to confer protein-protein interactions. They were subsequently found as a heme-binding motif in cellobiose dehydrogenase, an extracellular fungal oxidoreductase that degrades both lignin and cellulose, and in ethylbenzene dehydrogenase, an enzyme that aids in the anaerobic degradation of hydrocarbons. The domain interacts with sugars in the type 9 carbohydrate binding modules (CBM9), which are present in a variety of glycosyl hydrolases, and it can also be found at the N-terminus of sensor histidine kinases.
pfam01229	Glyco_hydro_39	4.55e-07	370	460	93	198	Glycosyl hydrolases family 39.
pfam06452	CBM9_1	9.25e-05	817	971	12	160	Carbohydrate family 9 binding domain-like. CBM9_1 is a C-terminal domain on bacterial xylanase proteins, and it is tandemly repeated in a number of family-members. The CBM9 module binds to amorphous and crystalline cellulose and a range of soluble di- and monosaccharides as well as to cello- and xylo- oligomers of different degrees of polymerization. Comparison of the glucose and cellobiose complexes during crystallisation reveals surprising differences in binding of these two substrates by CBM9-2. Cellobiose was found to bind in a distinct orientation from glucose, while still maintaining optimal stacking and electrostatic interactions with the reducing end sugar.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AHF94342.1	2.13e-177	19	993	46	1034
AHF90198.1	9.03e-137	48	985	52	998
AVM47149.1	2.19e-101	280	992	591	1307
AVM44759.1	1.41e-99	285	979	258	952
AVM46276.1	1.78e-98	275	992	422	1137

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000306	0.999036	0.000181	0.000138	0.000140	0.000144

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000720_02959.