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CAZyme Information: MGYG000000757_00479
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Negativicoccus massiliensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Negativicoccaceae; Negativicoccus; Negativicoccus massiliensis | |||||||||||
| CAZyme ID | MGYG000000757_00479 | |||||||||||
| CAZy Family | GT83 | |||||||||||
| CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7316; End: 8929 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT83 | 5 | 500 | 7.1e-93 | 0.9574074074074074 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1807 | ArnT | 2.03e-47 | 5 | 405 | 6 | 420 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| PRK13279 | arnT | 2.55e-31 | 7 | 383 | 4 | 395 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. |
| pfam13231 | PMT_2 | 1.03e-16 | 62 | 221 | 1 | 157 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| pfam02366 | PMT | 4.99e-11 | 34 | 223 | 32 | 232 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BBK24579.1 | 1.25e-133 | 7 | 504 | 27 | 527 |
| AOH39318.1 | 1.83e-124 | 13 | 533 | 17 | 544 |
| ARG00055.1 | 6.84e-124 | 12 | 526 | 10 | 535 |
| AXL21032.1 | 5.99e-120 | 13 | 525 | 8 | 534 |
| AXB83023.1 | 9.55e-120 | 12 | 512 | 7 | 521 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5EZM_A | 2.28e-25 | 29 | 310 | 54 | 344 | CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| B4TBG8 | 6.71e-31 | 13 | 337 | 7 | 337 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Salmonella heidelberg (strain SL476) OX=454169 GN=arnT PE=3 SV=1 |
| B7VBN0 | 3.06e-30 | 32 | 364 | 30 | 365 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain LESB58) OX=557722 GN=arnT PE=3 SV=1 |
| Q9HY61 | 7.56e-30 | 32 | 364 | 30 | 365 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=arnT PE=3 SV=1 |
| A6V1N8 | 1.38e-29 | 32 | 364 | 30 | 365 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain PA7) OX=381754 GN=arnT PE=3 SV=1 |
| Q57M54 | 1.83e-29 | 13 | 337 | 6 | 336 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Salmonella choleraesuis (strain SC-B67) OX=321314 GN=arnT PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999979 | 0.000015 | 0.000035 | 0.000000 | 0.000000 | 0.000001 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 5 | 27 |
| 86 | 108 |
| 113 | 135 |
| 173 | 195 |
| 208 | 230 |
| 257 | 276 |
| 289 | 308 |
| 312 | 331 |
| 343 | 362 |
| 366 | 383 |
| 396 | 418 |