CAZyme Information: MGYG000000759_01496

Basic Information

• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Corynebacterium
• CAZyme ID: MGYG000000759_01496
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
406		42647.54	4.0752

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000759	1836417	MAG	Bangladesh	Asia

• Gene Location: Start: 826; End: 2046 Strand: -

Full Sequence      

MWLVYPPFQTEGEEYCTLEGMKTPRILASLALVTALGACSPPPQEDTESQNSPPAAASSS
PAATQETQEETSQEAAPQQDIRAMAASVLMPPVTNYDDAKAKLEAGVGGIFIPSWADPNL
LQEEGRDINALRQEVGRDFEVSIDFEGGRVQRFSEVLGEYPAPQQMAAERSPQEVEQLAH
EIGTSLKAHGITVDFAPVLDVDGNALEVVGDRSFSTDPVQAGEYGAAFARGLDSAGVKAV
FKHFPGHGRASGDTHLAEAVTPPLEELEGHEFIPFKTALPQAPNAALMMGHLAVPGLGDG
QTPASILPEAYGLARETLQYDGPIYTDDIGGMKAIADSLPLADAVVTSLNAGADMPLWST
EGDINAVIDAVVGAVNDGRLPLERLADAARHVSAPPAGAAPKPAQD

Enzyme Prediction     

No EC number prediction in MGYG000000759_01496.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	141	357	2.3e-43	0.9351851851851852

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1472	BglX	2.98e-62	81	392	3	308	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam00933	Glyco_hydro_3	5.47e-54	106	392	31	313	Glycosyl hydrolase family 3 N terminal domain.
PRK05337	PRK05337	1.08e-45	107	357	26	278	beta-hexosaminidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QQU82600.1	5.86e-239	21	406	1	386
QRQ67786.1	6.82e-238	21	406	1	386
QQA98808.1	1.53e-234	21	406	1	386
QQN48100.1	3.08e-234	21	406	1	386
VEH73762.1	1.75e-199	1	392	1	393

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5IOB_A	4.59e-102	77	390	25	342	Crystalstructure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_B Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_C Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_D Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_E Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_F Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_G Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032],5IOB_H Crystal structure of beta-N-acetylglucosaminidase-like protein from Corynebacterium glutamicum [Corynebacterium glutamicum ATCC 13032]
4YYF_A	2.00e-65	82	380	42	343	ChainA, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_B Chain B, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155],4YYF_C Chain C, Beta-N-acetylhexosaminidase [Mycolicibacterium smegmatis MC2 155]
6GFV_A	3.01e-65	82	382	19	323	Mtuberculosis LpqI [Mycobacterium tuberculosis H37Rv],6GFV_B M tuberculosis LpqI [Mycobacterium tuberculosis H37Rv]
6K5J_A	3.00e-32	97	385	32	326	Structureof a glycoside hydrolase family 3 beta-N-acetylglucosaminidase from Paenibacillus sp. str. FPU-7 [Paenibacillaceae]
4GVF_A	2.90e-30	107	357	26	277	Crystalstructure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to GlcNAc [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4GVF_B Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to GlcNAc [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4GVG_A Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4GVG_B Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4GVH_A Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) covalently bound to 5-fluoro-GlcNAc. [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4GVH_B Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) covalently bound to 5-fluoro-GlcNAc. [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4HZM_A Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to N-[(3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl]butanamide [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2],4HZM_B Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to N-[(3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl]butanamide [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
L7N6B0	5.68e-64	82	382	62	366	Beta-hexosaminidase LpqI OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=lpqI PE=1 SV=1
A0A0H3M1P5	1.58e-63	82	382	62	366	Beta-hexosaminidase LpqI OS=Mycobacterium bovis (strain BCG / Pasteur 1173P2) OX=410289 GN=lpqI PE=3 SV=1
Q3SKU2	4.05e-32	97	357	18	281	Beta-hexosaminidase OS=Thiobacillus denitrificans (strain ATCC 25259) OX=292415 GN=nagZ PE=3 SV=1
B0U3L0	1.81e-31	130	373	46	292	Beta-hexosaminidase OS=Xylella fastidiosa (strain M12) OX=405440 GN=nagZ PE=3 SV=1
Q6D674	2.07e-31	107	357	26	277	Beta-hexosaminidase OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) OX=218491 GN=nagZ PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.014550	0.187432	0.796522	0.000145	0.001230	0.000105

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000759_01496.