CAZyme Information: MGYG000000760_00137

Basic Information

• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella
• CAZyme ID: MGYG000000760_00137
• CAZy Family: GH3
• CAZyme Description: Beta-hexosaminidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
946		104846.05	7.3946

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000760	2818339	MAG	Bangladesh	Asia

• Gene Location: Start: 136844; End: 139684 Strand: -

Full Sequence      

MKHILIVLLGLTIPCANVTRAQKPNQYSAKLKFYNLPKNKIYHKGWIDYNKNGKKDVYED
PTAGIDERIDNLISQMTLEEKTCQMVTLYGYKRVLQDDLPNEGWKQKLWKDGIGAIDEHL
NGFQQWGLPPSDNPWVWPASKHAWAINEVQRFFVEQTRLGIPVDFTNEGIRGVESFKATN
FPTQLGLGTTWNRKLIHQVGYITGREARLLGYTNVYAPILDVGRDQRWGRYEEVYGESPF
LVAELGIQMTRGLQTNYQVASTAKHFAAYSNNKGAREGMARVDPQMSPREVQNIHLYPWG
KVVSEAGLLGAMSSYNDYDGVPIQGSFHWLTEVLRQQFGFKGYVVSDSDALEYLFSKHRT
AANMKEAVYKAVMAGLNVRCTFRSPDSFVLPLRELVKEGRIPMKVIDERLSDILRVKFMV
GIFDRPYQMNLQAADKEVDGESHQQVALQASRESIVLLKNQNNTLPLNKASIKKIAVCGP
NANDATYALTHYGPLAVEVTTVFEGIRNKVGSDVEVTYTKGCDLVDAHWPESELLDYPMT
ADEQNEIDKAVEQVRQSDLAVVVLGGNSRTCGENKSRSSLELPGRQLQLLKAVQATGKTV
ILVLINGRPLSVNWADKFVPAIVEAWYPGSQGGTAVADVLFGDYNPGGKLTVTFPKTVGQ
IPFNFPSKPAALVDGGNKLGLHGNASRANGALYYFGHGLSYTTFKYSNLRLSAQNISATD
SVVVSCDITNTGKRAGDEVVQLYIQDVLSTVTTYEKNLRGFERVHLKPGETRILSFVIKP
EHLQLINEQYQHVVEPGDFKVMMGASSEDIRLEDTFTVTAPNASTVAKDRAHRLDVVAVP
ATPTAQYAVDGNTSTYWQGQTNASLTVSLPASEKLGSLTIVFAKGCSTDAEFTIQLSSGG
GQFLDVYTGKVSGHEQKLQINRSGVSDIRVLCQQGTLNIAEIKVDK

Enzyme Prediction     

No EC number prediction in MGYG000000760_00137.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH3	155	380	1.7e-60	0.9814814814814815

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK15098	PRK15098	2.72e-175	69	817	38	763	beta-glucosidase BglX.
PLN03080	PLN03080	1.60e-92	60	804	44	769	Probable beta-xylosidase; Provisional
COG1472	BglX	2.10e-72	142	508	41	393	Periplasmic beta-glucosidase and related glycosidases [Carbohydrate transport and metabolism].
pfam01915	Glyco_hydro_3_C	4.11e-71	455	701	1	216	Glycosyl hydrolase family 3 C-terminal domain. This domain is involved in catalysis and may be involved in binding beta-glucan. This domain is found associated with pfam00933.
pfam00933	Glyco_hydro_3	1.95e-61	77	416	1	316	Glycosyl hydrolase family 3 N terminal domain.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QIK60364.1	0.0	22	945	20	937
QIK54931.1	0.0	22	945	20	937
ALJ61698.1	0.0	34	945	29	941
QUT92742.1	0.0	34	945	29	941
QDO69526.1	0.0	34	942	29	938

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5YOT_A	5.38e-129	54	818	3	756	Isoprimeverose-producingenzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40],5YOT_B Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40],5YQS_A Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40],5YQS_B Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose [Aspergillus oryzae RIB40]
7EAP_A	4.07e-128	54	818	3	756	ChainA, Fn3_like domain-containing protein [Aspergillus oryzae RIB40]
5XXL_A	6.98e-128	65	811	10	745	Crystalstructure of GH3 beta-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],5XXL_B Crystal structure of GH3 beta-glucosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],5XXM_A Crystal structure of GH3 beta-glucosidase from Bacteroides thetaiotaomicron in complex with gluconolactone [Bacteroides thetaiotaomicron VPI-5482],5XXM_B Crystal structure of GH3 beta-glucosidase from Bacteroides thetaiotaomicron in complex with gluconolactone [Bacteroides thetaiotaomicron VPI-5482]
5XXN_A	3.76e-127	65	811	10	745	CrystalStructure of mutant (D286N) beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorose [Bacteroides thetaiotaomicron VPI-5482],5XXN_B Crystal Structure of mutant (D286N) beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorose [Bacteroides thetaiotaomicron VPI-5482],5XXO_A Crystal structure of mutant (D286N) GH3 beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorotriose [Bacteroides thetaiotaomicron VPI-5482],5XXO_B Crystal structure of mutant (D286N) GH3 beta-glucosidase from Bacteroides thetaiotaomicron in complex with sophorotriose [Bacteroides thetaiotaomicron VPI-5482]
5TF0_A	2.62e-123	66	811	10	744	CrystalStructure of Glycosil Hydrolase Family 3 N-Terminal Domain Protein from Bacteroides intestinalis [Bacteroides intestinalis DSM 17393],5TF0_B Crystal Structure of Glycosil Hydrolase Family 3 N-Terminal Domain Protein from Bacteroides intestinalis [Bacteroides intestinalis DSM 17393]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
T2KMH0	5.69e-141	158	808	62	711	Beta-xylosidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22130 PE=1 SV=1
P33363	4.55e-132	66	811	35	758	Periplasmic beta-glucosidase OS=Escherichia coli (strain K12) OX=83333 GN=bglX PE=3 SV=2
Q56078	3.12e-127	66	811	35	758	Periplasmic beta-glucosidase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=bglX PE=3 SV=2
T2KMH9	8.79e-122	58	811	29	748	Putative beta-xylosidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22230 PE=2 SV=1
A7LXU3	1.27e-95	141	828	106	786	Beta-glucosidase BoGH3B OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02659 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000668	0.949760	0.048848	0.000263	0.000223	0.000199

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000760_00137.