CAZyme Information: MGYG000000775_00380

Basic Information

• Species: Bifidobacterium sp900551485
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Bifidobacterium; Bifidobacterium sp900551485
• CAZyme ID: MGYG000000775_00380
• CAZy Family: GH31
• CAZyme Description: Alpha-xylosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
780	MGYG000000775_4|CGC2	87100.28	4.8127

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000775	1891758	MAG	Japan	Asia

• Gene Location: Start: 14026; End: 16368 Strand: +

Full Sequence      

MKFNNGYWLMRDGVQALFARDAYELHVDEQRKALSVLAPTSMIHERANTLNQPAFNVEIT
APSEGVIRVRATHWRGGAQGIGFPLNEDESPRDYVSVSQHLNGDGEAGEQGATATLKSGA
LEATVTKGPWSLVFTADGTTLTKSEGKSLAHFSLTDLANVSAEPVGEFGVTPTGLAKDES
KTFTSVQLALGVGESVYGLGERFGSFVKNGQSIDIWNEDGGTASEQGYKNIPFYMTSNGY
GVLINDRGHVSFEIGTVNTEAVQCSVPGESIDFCIIYGPTPKQILDRYTKLVGRPANVPA
WSYGLWLTTSFTTTYDEQTINSFIDGMADRGIPLSAFHYDCYWMREFHWTDFEWDRRYFG
DIEATLRRLHTDKGLHLCAWINPYLGQNGTMFDEGRKLGYLVKNPDGTIWQTDNWQAGMA
LVDFTNPAAREWFKGKVKKLLAQGIDAIKTDFGERIPRDVVWFDDAPKLSMHNWYTELYN
QTVFEAIEETYGQGNACLFARSATVGGQQYPVHWGGDCESTFNGMAQTLRAGLSLTSSGF
GFWSHDIGGFEGAFPDPAVYKRWVAFGMLSSHSRLHGSTVYRVPWLFDEADEKNGVINAP
GQTAVDVLRQFTLLKLSLMPYLYQQGLQPHLNGTPLMRSMFVEFPDDPACRALDKQYMLG
PDLLVAPVFSYSGEVEYYLPRGSWQNWFTGEIVRSEHGVWRHEQHGFDSIPLWIRDGSVI
VTNPEATSPEYDYAEDVQVRAFLDDVHEASATVTRLDGSTVEFRTRRTDDGVELTRSDTR

Enzyme Prediction     

EC	3.2.1.177

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH31	275	720	3.4e-123	0.9929742388758782

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1501	YicI	0.0	8	760	1	709	Alpha-glucosidase, glycosyl hydrolase family GH31 [Carbohydrate transport and metabolism].
PRK10658	PRK10658	0.0	1	717	1	665	putative alpha-glucosidase; Provisional
cd06593	GH31_xylosidase_YicI	1.09e-166	293	618	1	308	alpha-xylosidase YicI-like. YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a homohexamer (a trimer of dimers). All GH31 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. The YicI family corresponds to subgroup 4 in the Ernst et al classification of GH31 enzymes.
pfam01055	Glyco_hydro_31	1.04e-151	275	720	2	442	Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases.
PRK10426	PRK10426	2.81e-70	193	692	81	598	alpha-glucosidase; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ATU19896.1	0.0	1	776	1	779
AIZ16892.1	0.0	1	777	1	780
ASW24636.1	0.0	1	777	1	780
AXR42366.1	0.0	1	780	1	783
AJE06671.1	0.0	1	780	1	783

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2F2H_A	2.99e-248	1	775	1	726	Structureof the YicI thiosugar Michaelis complex [Escherichia coli],2F2H_B Structure of the YicI thiosugar Michaelis complex [Escherichia coli],2F2H_C Structure of the YicI thiosugar Michaelis complex [Escherichia coli],2F2H_D Structure of the YicI thiosugar Michaelis complex [Escherichia coli],2F2H_E Structure of the YicI thiosugar Michaelis complex [Escherichia coli],2F2H_F Structure of the YicI thiosugar Michaelis complex [Escherichia coli]
1XSI_A	3.54e-248	1	775	1	726	Structureof a Family 31 alpha glycosidase [Escherichia coli],1XSI_B Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSI_C Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSI_D Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSI_E Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSI_F Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSJ_A Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSJ_B Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSJ_C Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSJ_D Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSJ_E Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSJ_F Structure of a Family 31 alpha glycosidase [Escherichia coli],1XSK_A Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate [Escherichia coli],1XSK_B Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate [Escherichia coli],1XSK_C Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate [Escherichia coli],1XSK_D Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate [Escherichia coli],1XSK_E Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate [Escherichia coli],1XSK_F Structure of a Family 31 alpha glycosidase glycosyl-enzyme intermediate [Escherichia coli]
1WE5_A	6.13e-237	2	775	2	726	CrystalStructure of Alpha-Xylosidase from Escherichia coli [Escherichia coli],1WE5_B Crystal Structure of Alpha-Xylosidase from Escherichia coli [Escherichia coli],1WE5_C Crystal Structure of Alpha-Xylosidase from Escherichia coli [Escherichia coli],1WE5_D Crystal Structure of Alpha-Xylosidase from Escherichia coli [Escherichia coli],1WE5_E Crystal Structure of Alpha-Xylosidase from Escherichia coli [Escherichia coli],1WE5_F Crystal Structure of Alpha-Xylosidase from Escherichia coli [Escherichia coli]
5F7C_A	4.52e-92	194	740	202	737	Crystalstructure of Family 31 alpha-glucosidase (BT_0339) from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],5F7C_B Crystal structure of Family 31 alpha-glucosidase (BT_0339) from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],5F7C_C Crystal structure of Family 31 alpha-glucosidase (BT_0339) from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],5F7C_D Crystal structure of Family 31 alpha-glucosidase (BT_0339) from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
5F7U_A	2.92e-63	105	723	171	805	Cycloalternan-formingenzyme from Listeria monocytogenes in complex with pentasaccharide substrate [Listeria monocytogenes EGD-e]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P31434	1.58e-247	1	775	1	726	Alpha-xylosidase OS=Escherichia coli (strain K12) OX=83333 GN=yicI PE=1 SV=2
Q5AW25	5.40e-229	1	774	1	755	Alpha-xylosidase OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=agdD PE=1 SV=1
P96793	6.19e-201	1	774	1	729	Alpha-xylosidase XylQ OS=Lactiplantibacillus pentosus OX=1589 GN=xylQ PE=1 SV=1
Q9F234	2.81e-55	197	730	150	684	Alpha-glucosidase 2 OS=Bacillus thermoamyloliquefaciens OX=1425 PE=3 SV=1
P32138	2.19e-43	149	695	80	646	Sulfoquinovosidase OS=Escherichia coli (strain K12) OX=83333 GN=yihQ PE=1 SV=3

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000066	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000775_00380.