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CAZyme Information: MGYG000000781_02257

You are here: Home > Sequence: MGYG000000781_02257

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phocaeicola sp900541515
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900541515
CAZyme ID MGYG000000781_02257
CAZy Family PL12
CAZyme Description Heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
709 MGYG000000781_47|CGC1 80911.8 4.7528
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000781 3237958 MAG China Asia
Gene Location Start: 4341;  End: 6470  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 4.2.2.8

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL12 424 559 1.1e-56 0.9923664122137404

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16889 Hepar_II_III_N 1.40e-129 51 403 1 344
Heparinase II/III N-terminus. This is the N-terminal domain of heparinase II/III proteins. It is a toroid-like domain.
pfam07940 Hepar_II_III 9.42e-21 414 590 2 179
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QQA07253.1 0.0 1 709 1 707
QUT42640.1 0.0 1 709 1 707
QIU95112.1 9.85e-257 9 709 18 729
QDH54998.1 4.56e-255 1 709 1 728
QRQ56238.1 3.69e-254 1 709 1 728

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FNV_A 1.85e-170 1 709 1 702
CrystalStructure of Heparinase III [Bacteroides thetaiotaomicron VPI-5482]
5JMD_A 6.19e-113 43 709 11 655
HeparinaseIII-BT4657 gene product, Methylated Lysines [Bacteroides thetaiotaomicron VPI-5482]
5JMF_A 1.25e-102 43 709 11 655
HeparinaseIII-BT4657 gene product [Bacteroides thetaiotaomicron VPI-5482]
4MMH_A 8.59e-82 46 662 5 597
Crystalstructure of heparan sulfate lyase HepC from Pedobacter heparinus [Pedobacter heparinus]
4MMI_A 1.20e-81 51 662 10 597
Crystalstructure of heparan sulfate lyase HepC mutant from Pedobacter heparinus [Pedobacter heparinus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q89YR9 1.01e-169 1 709 1 702
Heparin-sulfate lyase OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=hepC PE=1 SV=1
C7EXL6 3.25e-112 46 709 25 666
Heparin-sulfate lyase OS=Bacteroides stercoris OX=46506 GN=hepC PE=1 SV=1
Q59289 6.73e-81 46 662 29 621
Heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000111 0.070524 0.929278 0.000037 0.000041 0.000031

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000781_02257.