CAZyme Information: MGYG000000784_00376

Basic Information

• Species: CAG-417 sp000432835
• Lineage: Bacteria; Firmicutes; Bacilli; RF39; UBA660; CAG-417; CAG-417 sp000432835
• CAZyme ID: MGYG000000784_00376
• CAZy Family: GT51
• CAZyme Description: Monofunctional biosynthetic peptidoglycan transglycosylase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
938		103842.73	9.3682

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000784	1269692	MAG	China	Asia

• Gene Location: Start: 41640; End: 44456 Strand: +

Full Sequence      

MAKRIKRKNDVEKTRKFETKDLKGKRTTSKESNNTSSKTMKIILLVILVLTLILCFIKLG
AICTVVLAFGILIILGIYALLKSSSLSRKKKKVINIILIIILTLGIICLVAFSAFLIYIT
VSAPKFNPDNLDTQELSIMYDSNGQVIAKLGAEKREKVKYDELPQVLIDAIVSTEDSRFY
QHNGFDAPRFFKATLKQLLGDNSAGGASTLSMQVVKNSFTDASQDSGIKGIIRKFTDIYL
AVFKLEKNYTKEEIIEFYVNNHYLGGNIYGVEEASQAYFNKSVGELNLSEATIIAGMFKN
PGGYSPTLHPDNAAARRKTVLYLMRRHGYITEEEQKLANSIPVASLTKDASGNSTSNGVS
PYQSYIDTVVKELDKKYNVNPYKTSLLIYTNMDRSKQEGINRVFNEESYKWVDDQIQSGV
SVLDSQTGKLLAVGAGRNRSVGDYNFATDIKRQPGSTAKPLFDYGPGIEYNNWSTYQQFV
DEPYTYTGGRKISNWDNGYMGQMTLRKALSLSRNIPALKAFQQVDKSKIIQFVTNLGIQP
EVENGTIHEAHSIGAFTGVNPVQMSAAYAAFSNGGYYNEPYSVSKITYRETGNTIEHKSE
KKKAMSDSTAYMIASVLQDVKLNGGGTITNYAVKTGTTNFDDAYVKSKGLPGDAIRDSWA
VGFSTKTVVAMWYGYNESTKEHCMRNLPSSIAKDKLYRTLVKEVVESNREEFKMPDSVVK
LPIISGSNPAKVAPTGYSGSVVYELFKKDHQPNGTSSGEKENKLATPSNLKVTYSDGTVT
ISWGAVQNPYTEYGTFGYNVYFGNTLLGFTESTSFTKQLANPYGTYKVVATYQSYSGINS
DAASYTLKEASNTKPTTPEKTELKYTIKYYCGTSLIEEVVKTVQTSSNGYYLKDSDIVDS
TKIPDTCSQTDRTFSSNIPGSITNGSTITVTYKEKATQ

Enzyme Prediction     

No EC number prediction in MGYG000000784_00376.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT51	143	324	1e-56	0.9887005649717514

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG0744	MrcB	5.90e-145	110	739	29	644	Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009	MrcA	1.33e-92	110	769	18	781	Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
pfam00912	Transgly	9.60e-71	143	325	1	177	Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
COG4953	PbpC	8.95e-63	110	780	7	622	Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
PRK14850	PRK14850	1.44e-48	131	683	141	675	penicillin-binding protein 1b; Provisional

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AWI12666.1	5.27e-159	89	853	26	782
APH04640.1	9.53e-159	104	783	42	713
QNF30636.1	1.42e-153	101	783	44	722
BBU39970.1	2.00e-153	101	783	35	707
ASS91702.1	2.80e-153	101	783	35	707

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3DWK_A	8.56e-92	139	730	10	608	ChainA, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_B Chain B, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_C Chain C, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL],3DWK_D Chain D, Penicillin-binding protein 2 [Staphylococcus aureus subsp. aureus COL]
2OLU_A	3.45e-88	123	730	3	617	StructuralInsight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Apoenzyme [Staphylococcus aureus],2OLV_A Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus],2OLV_B Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex [Staphylococcus aureus]
3ZG8_B	2.48e-57	244	690	2	447	CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3ZG7_B	1.45e-53	244	690	2	447	CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]
3UDF_A	7.38e-48	139	679	23	692	ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P39793	1.15e-138	123	783	63	727	Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
Q00573	4.40e-95	102	676	18	601	Penicillin-binding protein 1A (Fragment) OS=Streptococcus oralis OX=1303 GN=ponA PE=3 SV=1
Q04707	1.67e-90	102	720	18	642	Penicillin-binding protein 1A OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=ponA PE=1 SV=2
Q8DR59	1.19e-89	102	720	18	642	Penicillin-binding protein 1A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=pbpA PE=1 SV=1
P38050	6.39e-82	106	738	15	630	Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999863	0.000129	0.000001	0.000000	0.000000	0.000003

TMHMM  Annotations     

start	end
42	61
65	87
94	116