CAZyme Information: MGYG000000790_00067

Basic Information

• Species: Fusobacterium nucleatum_E
• Lineage: Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae; Fusobacterium; Fusobacterium nucleatum_E
• CAZyme ID: MGYG000000790_00067
• CAZy Family: GH135
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
608	MGYG000000790_3|CGC1	69408.64	7.5457

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000790	2081813	MAG	China	Asia

• Gene Location: Start: 16689; End: 18515 Strand: -

Full Sequence      

MKNQLKRILPFFIIGITSISYGKNISNVNTLNKIQVNIEYMRGFSKNHDYKNISANQSVI
MPAFRWTGDSGVNASFWNGITDIGGGLIPYVAFGSYVGTSWRTQQLVQRDADAKQIQQNN
QAGIKSIGYTYTVNSTRDLNEVYADIDNFVNFYGRENISGYFVDEVMGGATQNQIEYMAN
IYNYIKTKYPEMLVIANNGWGIRDGIAPYADIWLTREVTADEYLNHYREPTSEFEKNPEN
ASHIYHVIHSASPEQYEEILRLSRERNAGRVFITSDTNAYPSGYDDLPTYFEDLMLTINN
FTPKSNSLFSSDSRASDKVTIEMPRSKVDLDLTKTLRNISYKNLENTKDGEYKIDIAYMQ
NYGGEYKDKESNVKYKSDSDGILLNTSKDFGKLTLGIAFGSQKSNVNYKEKYGGVKEKIT
SYEFGLNGKYDFNENIDLATNLIYSTNKHKFNTSNGLGAINGVNYKSKILDFNTRLGYKF
LFDNGYVKPYIGLGITRVKEEDIDKLKFSDTSKTALNGSLGVYGEKSFGKFYLFGDLEYE
HRFSNKSYHGVRTYSTRYEIAGLDYKKGVVNFELGLRYNITDNFKINVAYQLSENKNNLM
KFGFGFEF

Enzyme Prediction     

No EC number prediction in MGYG000000790_00067.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH135	114	294	1.1e-23	0.7721518987341772

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam12138	Spherulin4	4.05e-21	110	295	41	235	Spherulation-specific family 4. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 250 and 398 amino acids in length. There is a conserved NPG sequence motif and there are two completely conserved G residues that may be functionally important. Starvation will often induce spherulation - the production of spores - and this process may involve DNA-methylation. Changes in the methylation of spherulin4 are associated with the formation of spherules, but these changes are probably transient. Methylation of the gene accompanies its transcriptional activation, and spherulin4 mRNA is only detectable in late spherulating cultures and mature spherules. It is a spherulation-specific protein.
pfam03797	Autotransporter	3.59e-18	357	591	1	254	Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
smart00869	Autotransporter	9.43e-16	359	598	1	267	Autotransporter beta-domain. Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
TIGR01414	autotrans_barl	2.04e-08	357	606	165	427	outer membrane autotransporter barrel domain. A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
pfam13505	OMP_b-brl	0.010	389	553	18	164	Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASQ47822.1	3.00e-241	34	608	142	707
QUB96211.1	1.34e-236	34	608	139	704
BBM45129.1	1.20e-157	56	603	219	760
BBM57219.1	3.77e-156	56	603	219	760
BBM53111.1	2.33e-67	1	431	1	451

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.017057	0.965678	0.016271	0.000335	0.000310	0.000317

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000790_00067.