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CAZyme Information: MGYG000000820_00083

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Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA9506 sp003506415
Lineage Bacteria; Firmicutes_A; Clostridia; Monoglobales_A; UBA9506; UBA9506; UBA9506 sp003506415
CAZyme ID MGYG000000820_00083
CAZy Family GH57
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
513 MGYG000000820_1|CGC1 59246.16 4.9318
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000820 2712076 MAG China Asia
Gene Location Start: 77272;  End: 78813  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000820_00083.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH57 5 349 1.5e-31 0.7963446475195822

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd10794 GH57N_PfGalA_like 3.03e-35 4 159 1 153
N-terminal catalytic domain of alpha-galactosidase; glycoside hydrolase family 57 (GH57). Alpha-galactosidases (GalA, EC catalyze the hydrolysis of alpha-1,6-linked galactose residues from oligosaccharides and polymeric galactomannans. Based on sequence similarity, the majority of eukaryotic and bacterial GalAs have been classified into glycoside hydrolase family GH27, GH36, and GH4, respectively. This subfamily is represented by a novel type of GalA from Pyrococcus furiosus (PfGalA), which belongs to the GH57 family. PfGalA is an extremely thermo-active and thermostable GalA that functions as a bacterial-like GalA, however, without the capacity to hydrolyze polysaccharides. It specifically catalyzes the hydrolysis of para-nitrophenyl-alpha-galactopyranoside, and to some extent that of melibiose and raffinose. PfGalA has a pH optimum between 5.0-5.5.
pfam03065 Glyco_hydro_57 4.93e-21 6 220 23 252
Glycosyl hydrolase family 57. This family includes alpha-amylase (EC:, 4--glucanotransferase (EC:2.4.1.-) and amylopullulanase enzymes.
cd01022 GH57N_like 5.68e-18 6 223 3 247
N-terminal catalytic domain of heat stable retaining glycoside hydrolase family 57. Glycoside hydrolase family 57(GH57) is a chiefly prokaryotic family with the majority of thermostable enzymes coming from extremophiles (many of these are archaeal hyperthermophiles), which exhibit the enzyme specificities of alpha-amylase (EC, 4-alpha-glucanotransferase (EC, amylopullulanase (EC, and alpha-galactosidase (EC This family also includes many hypothetical proteins with uncharacterized activity and specificity. GH57s cleave alpha-glycosidic bonds by employing a retaining mechanism, which involves a glycosyl-enzyme intermediate, allowing transglycosylation.
cd10793 GH57N_TLGT_like 2.51e-14 21 138 19 135
N-terminal catalytic domain of 4-alpha-glucanotransferase; glycoside hydrolase family 57 (GH57). 4-alpha-glucanotransferase (TLGT, EC plays a key role in the maltose metabolism. It catalyzes the disproportionation of amylose and the formation of large cyclic alpha-1,4-glucan (cycloamylose) from linear amylose. TLGT functions as a homodimer. Each monomer is composed of two domains, an N-terminal catalytic domain with a (beta/alpha)7 barrel fold and a C-terminal domain with a twisted beta-sandwich fold. Some family members have been designated as alpha-amylases, such as the heat-stable eubacterial amylase from Dictyoglomus thermophilum (DtAmyA) and the extremely thermostable archaeal amylase from Pyrococcus furiosus(PfAmyA). However, both of these proteins are 4-alpha-glucanotransferases. DtAmyA was shown to have transglycosylating activity and PfAmyA exhibits 4-alpha-glucanotransferase activity.
COG1449 COG1449 2.24e-12 36 487 152 549
Alpha-amylase/alpha-mannosidase, GH57 family [Carbohydrate transport and metabolism].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QDT00377.1 8.69e-254 1 513 1 511
AVM45997.1 3.70e-44 8 446 12 455
AHF90539.1 3.54e-42 8 419 11 426
EHR78079.1 1.72e-16 5 168 4 167
CAT70989.1 5.73e-15 5 178 4 177

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      help

has no Swissprot hit.

SignalP and Lipop Annotations help

This protein is predicted as OTHER

1.000075 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000820_00083.