CAZyme Information: MGYG000000847_00819

Basic Information

• Species: Acidaminococcus sp900538365
• Lineage: Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Acidaminococcus; Acidaminococcus sp900538365
• CAZyme ID: MGYG000000847_00819
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
377	MGYG000000847_12|CGC1	41015.36	9.7087

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000847	2084328	MAG	China	Asia

• Gene Location: Start: 49069; End: 50202 Strand: -

Full Sequence      

MRIFISAGEASGDLHAAALTREILSLAPDAEVFGMGGDALRSAGGEVIFDYKDNSVMGFV
EVLRKLPALFRLRDAFRQVMVERKPDIFVTVDYPDFNMRVAKVAKQLGIPVFCFIPPSAW
AWRRGRAKMVARLAARVACIYPFAYEVYKEAGAPVEFVGNPLVDIVKPTMSQAEAQKAVG
KRTGHPLILLLPGSRQGELRGVLPVMLEALPLIKKARPDADFILQKAPNVDRRKLEAALA
ASKVPVPIVEDHPYDTMGACDAALATSGTVVLEAALMNLPSVICYKASPLSMAIAKALVK
VKYAGLPNLLAGREILPELIQEKMTPENMARHVLRFLDPSEGTKVHQDLREAICKLGAPG
AVKRTAALILETAKEKK

Enzyme Prediction     

No EC number prediction in MGYG000000847_00819.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	3	351	4.8e-121	0.9774011299435028

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK00025	lpxB	1.80e-133	1	377	2	379	lipid-A-disaccharide synthase; Reviewed
COG0763	LpxB	2.00e-117	1	375	2	381	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
pfam02684	LpxB	4.11e-91	3	371	1	373	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
PRK14089	PRK14089	4.30e-49	1	329	2	309	lipid-A-disaccharide synthase.
PRK01021	lpxB	1.14e-46	4	330	230	563	lipid-A-disaccharide synthase; Reviewed

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEQ21864.1	3.13e-254	1	377	1	377
ADB48042.1	6.50e-187	2	375	3	376
BBG63223.1	1.05e-142	2	376	3	377
QNP77898.1	1.05e-142	2	376	3	377
QTV78315.1	3.60e-137	2	377	8	383

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8S_A	7.10e-53	1	373	7	381	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]
5W8N_A	1.96e-52	1	373	7	381	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q74AT9	8.41e-101	2	371	8	378	Lipid-A-disaccharide synthase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) OX=243231 GN=lpxB PE=3 SV=1
Q39T49	7.66e-99	2	377	8	384	Lipid-A-disaccharide synthase OS=Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15) OX=269799 GN=lpxB PE=3 SV=1
Q1D393	7.84e-93	2	371	6	376	Lipid-A-disaccharide synthase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxB PE=3 SV=1
B3E4H8	2.00e-90	2	370	8	377	Lipid-A-disaccharide synthase OS=Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ) OX=398767 GN=lpxB PE=3 SV=1
B8JE78	2.54e-88	2	370	10	379	Lipid-A-disaccharide synthase OS=Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258) OX=455488 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000054	0.000002	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000847_00819.