CAZyme Information: MGYG000000853_00923

Basic Information

• Species: Prevotella sp900549175
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900549175
• CAZyme ID: MGYG000000853_00923
• CAZy Family: GH98
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1045	MGYG000000853_35|CGC1	116222.85	5.74

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000853	3157276	MAG	China	Asia

• Gene Location: Start: 15558; End: 18695 Strand: -

Full Sequence      

MLQNMKTRLLKLFVLLATFTLAAQTVTAQERRPIDERHPLWLIHVDIWNQADPQKIIDLI
PDDIKPYVCLNLSLSCSYDKDKDVYMRPQNGVRTFKSWATVCQANKMWFTCQPASGGHTH
IKDDDLETFEYFFKRYPNFLGWNFAEQFWGFDEPGDKSSSSQIDRLRLFSKLIPMSHRYG
GFLTISFCGNIWSHGLNPVGMMKRNSDLLQACRDYPEAILWLYKYTTSSCFYNNESVTFS
PFISGLAKNYGVRYDNCGWNGALEAILGENHGRKYPTAAGIGTVMEQTCVNGGAVWDGPE
LIWTEDFKNLSNSTVDGYTRRNWGRFPGFDNAWIDMFRKIIDGMMYIPTREEVVGRTKIV
VVNDVNSGSDEDKYASWGSLYDGLYKQDDPFNKDDGQWMNNFWYLKKTGRYGTIPVAIEL
YDDLAKTIPTVVKKSERTKRWPDESRKVAEYNSMYPEMSTGDLFVSRHKNQLVAYTPYTY
LNSKTTASAALAMEYNTCDSLQLTFGLLSSGIIREYAGRLDCYLNNYRSDVSTNVSDILT
IKGASARPSYTMKRRGTATARGTEKWDEATGTYTLEVKHNGPVDISIECAGTATGRSTDT
LPAEALTAGLPLQPGDYAGELIIEAEDMDYKSVKDCVVLPYYNRPDVRGFSGNGFIETGT
NRAGSLRHTTDKLKAGTYDVTVRYSSPSKAGRMKAVMGGKEYTLQCDKTETNQWRKVTFT
ATATAGTNSLTLTNTDGADMMIDQIVYAPEGTETEEYLVTIRDVDHGRVTADTGTAAEGT
TVSLTAEPEEGYALVGWEVIHGNVTIGDDLTFIMPDDNVTLRPLFAEAALVYKLDFTKVG
SGAMPEGWRAVQGGDDVHEYPNTYGQGARTFAGFNGYQGKALYWREKNAEYGRLDGYRLT
LAPGAYKLKYAVAAWKGEPNYKVAVLDETGKAVVSSPTRSAAPNANGSSSSDVSSAVCHE
LDVNITKAGNYIISFTNAESGFSEFLLLECKLSDCAIAGIGSIVAGNGEDIIGIYGIDGV
KRHEMQKGLNILQLRGGKTKKVICR

Enzyme Prediction     

EC	3.2.1.8

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH98	28	344	3.3e-84	0.9877675840978594

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam08306	Glyco_hydro_98M	3.61e-91	27	343	4	326	Glycosyl hydrolase family 98. This domain is the putative catalytic domain of glycosyl hydrolase family 98 proteins.
pfam08307	Glyco_hydro_98C	2.07e-13	350	587	1	267	Glycosyl hydrolase family 98 C-terminal domain. This putative domain is found at the C-terminus of glycosyl hydrolase family 98 proteins. This domain is not expected to form part of the catalytic activity.
pfam18998	Flg_new_2	2.17e-10	757	821	1	66	Divergent InlB B-repeat domain. This family of domains are found in bacterial cell surface proteins. They are often found in tandem array. This domain is closely related to pfam09479.
cd04083	CBM35_Lmo2446-like	5.48e-04	649	685	22	58	Carbohydrate Binding Module 35 (CBM35) domains similar to Lmo2446. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes. Some CBM35 domains belonging to this family are appended to glycoside hydrolase (GH) family domains, including glycoside hydrolase family 31 (GH31), for example the CBM35 domain of Lmo2446, an uncharacterized protein from Listeria monocytogenes EGD-e. These CBM35s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. GH31 has a wide range of hydrolytic activities such as alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, or alpha-1,4-glucan lyase, cleaving a terminal carbohydrate moiety from a substrate that may be a starch or a glycoprotein. Most characterized GH31 enzymes are alpha-glucosidases.
cd02795	CBM6-CBM35-CBM36_like	0.002	623	746	2	123	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily. Carbohydrate binding module family 6 (CBM6, family 6 CBM), also known as cellulose binding domain family VI (CBD VI), and related CBMs (CBM35 and CBM36). These are non-catalytic carbohydrate binding domains found in a range of enzymes that display activities against a diverse range of carbohydrate targets, including mannan, xylan, beta-glucans, cellulose, agarose, and arabinans. These domains facilitate the strong binding of the appended catalytic modules to their dedicated, insoluble substrates. Many of these CBMs are associated with glycoside hydrolase (GH) domains. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. CBM36s are calcium-dependent xylan binding domains. CBM35s display conserved specificity through extensive sequence similarity, but divergent function through their appended catalytic modules. This alignment model also contains the C-terminal domains of bacterial insecticidal toxins, where they may be involved in determining insect specificity through carbohydrate binding functionality.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AGB29515.1	0.0	21	1042	13	1032
BAV06735.1	1.93e-173	31	752	35	751
QUT78600.1	6.64e-172	26	746	223	935
QUT26887.1	6.64e-172	26	746	223	935
AOZ99817.1	1.07e-171	15	690	17	679

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2WMH_A	9.26e-16	327	587	307	581	Crystalstructure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 in complex with the H- disaccharide blood group antigen. [Streptococcus pneumoniae TIGR4]
2WMF_A	2.13e-15	327	587	307	581	Crystalstructure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 (Sp4GH98) in its native form. [Streptococcus pneumoniae TIGR4]
2WMG_A	2.81e-15	327	587	307	581	Crystalstructure of the catalytic module of a family 98 glycoside hydrolase from Streptococcus pneumoniae TIGR4 (Sp4GH98) in complex with the LewisY pentasaccharide blood group antigen. [Streptococcus pneumoniae TIGR4]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000348	0.998933	0.000166	0.000198	0.000175	0.000155

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000853_00923.