CAZyme Information: MGYG000000854_01650

Basic Information

• Species: Paraprevotella sp900548345
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Paraprevotella; Paraprevotella sp900548345
• CAZyme ID: MGYG000000854_01650
• CAZy Family: CBM6
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1012	MGYG000000854_26|CGC1	112758.24	4.742

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000854	2733305	MAG	China	Asia

• Gene Location: Start: 24397; End: 27435 Strand: -

Full Sequence      

MKKNLWIKSLLMLCCGFSLHAQAQKRTFVHPGITYTQADLDRMKAMVEARQEPFYTTYLN
LLDDRYSKPGNGAYEDITQIKEGRFNATIGSDGRRAHDMALLYHITGDRKYADDAVARLN
RYKRLTNASCRGTAPLDNGKIYMLIEAAELLRDYEGWAEEDREAFKKMLVYPFYSTKVSA
ESHKSLTDDNNDVSFYWNIYNFDPGRFGNQGLFAARGLMAMGIFLDNDTIYERGYRYLTG
LPARTDDLPLRMGPPIQGSLISEDEFKCDYNVSWPSTGEPYYSDEVLKYYIYRNGQCQES
CRDQGHTMGGIGNYTAIAEMTWNQGDTLYSCLDNRILKGIEFNIRYNLSGIQSFDDQPEP
WEPSAYTDNEDECSFENNKFYKAVSRSKRWAAKSMAYGDRGKVFGTGGWKTQALDHYRVR
AGLPAEDMVWLQRAYDKMMADYGCENWGVAPNWFYEWAGWGTLTKKRTEWMAGDAGTWKD
GKRMSGIPTVPCTVKAADYDYYTENGEMHTYHNVGTKSGTVYRADGTVELACEGDDVYVT
AMEDGEWMSYTLIFPAPEYNTATGLEKKYNVYATYRATASGTSLFAAVDGGKKIGKKMEP
TGEWTEKLLGTLTVKCGAAVLRVYVQGKSGTVELKNLRVAPLEQVEQLAVNLQERAVSVK
VYDANGNDKTEEWEAAVTAASDGIKDQPISLKNQYFMVYDFGEDGIDLNKVVMYNDGAVQ
DTREQAKVLGSTADGPYTGSWNVGAASDFMRTNGTVYGGVSVIDDSWVTEDGSMGSYAVG
PVGRYRYMAVYNWSAYCRISEVEVWSGVNMSVEKEDEEPSAEWGGQPVLSLTSPKWYAGD
TELAARTVSPRFTLQNTGDADLVVTGVTSLTAPWSTSFDLQEGSVLAPGETYGFNFVFTP
ERIGVWEEEFAVETNAGRKAIRLVGDGIHATSVSGVTGEPRVSVTSPRGNTLSIRTVEDV
AYRVSGVSGMVMNEGRVAAFRPCELRLPCGIYIVSVFTSGGMQAYKLVVGAE

Enzyme Prediction     

No EC number prediction in MGYG000000854_01650.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04080	CBM6_cellulase-like	2.43e-06	490	627	1	133	Carbohydrate Binding Module 6 (CBM6); appended to glycoside hydrolase (GH) domains, including GH5 (cellulase). This family includes carbohydrate binding module 6 (CBM6) domains that are appended to several glycoside hydrolase (GH) domains, including GH5 (cellulase) and GH16, as well as to coagulation factor 5/8 carbohydrate-binding domains. CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. The CBM6s are appended to GHs that display a diversity of substrate specificities. For some members of this family information is available about the specific substrates of the appended GH domains. It includes the CBM domains of various enzymes involved in cell wall degradation including, an extracellular beta-1,3-glucanase from Lysobacter enzymogenes encoded by the gluC gene (its catalytic domain belongs to the GH16 family), the tandem CBM domains of Pseudomonas sp. PE2 beta-1,3(4)-glucanase A (its catalytic domain also belongs to GH16), and a family 6 CBM from Cellvibrio mixtus Endoglucanase 5A (CmCBM6) which binds to the beta1,4-beta1,3-mixed linked glucans lichenan, and barley beta-glucan, cello-oligosaccharides, insoluble forms of cellulose, the beta1,3-glucan laminarin, and xylooligosaccharides, and the CBM6 of Fibrobacter succinogenes S85 XynD xylanase, appended to a GH10 domain, and Cellvibrio japonicas Cel5G appended to a GH5 (cellulase) domain. GH5 (cellulase) family includes enzymes with several known activities such as endoglucanase, beta-mannanase, and xylanase, which are involved in the degradation of cellulose and xylans. GH16 family includes enzymes with lichenase, xyloglucan endotransglycosylase (XET), and beta-agarase activities. CBM6 is an unusual CBM as it represents a chimera of two distinct binding sites with different modes of binding: binding site I within the loop regions and binding site II on the concave face of the beta-sandwich fold. For CmCBM6 it has been shown that these two binding sites have different ligand specificities.
pfam07610	DUF1573	9.70e-05	847	923	18	92	Protein of unknown function (DUF1573). These hypothetical proteins, from bacteria such as Rhodopirellula baltica, Bacteroides thetaiotaomicron, and Porphyromonas gingivalis, share a region of conserved sequence towards their N-termini.
NF012200	choice_anch_D	6.06e-04	839	900	32	88	choice-of-anchor D domain. This HMM describes a repeat domain just over 100 amino acids long and usually found in tandem copies. Members appear to be extracellular proteins that have some C-terminal anchoring domain, such as type IX secrection (T9SS) or PEP-CTERM.
pfam05426	Alginate_lyase	8.06e-04	89	234	54	193	Alginate lyase. This family contains several bacterial alginate lyase proteins. Alginate is a family of 1-4-linked copolymers of beta -D-mannuronic acid (M) and alpha -L-guluronic acid (G). It is produced by brown algae and by some bacteria belonging to the genera Azotobacter and Pseudomonas. Alginate lyases catalyze the depolymerization of alginates by beta -elimination, generating a molecule containing 4-deoxy-L-erythro-hex-4-enepyranosyluronate at the nonreducing end. This family adopts an all alpha fold.
pfam10633	NPCBM_assoc	0.006	844	900	3	60	NPCBM-associated, NEW3 domain of alpha-galactosidase. The English-language version of the first reference can be found on pages 388-399 of the above. This domain has been named NEW3 but its actual function is not known. It is found on proteins which are bacterial galactosidases. The domain is associated with the NPCBM family, pfam08305, a novel putative carbohydrate binding module found at the N-terminus of glycosyl hydrolases.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNL37058.1	3.94e-229	22	637	22	634
QUT82474.1	6.29e-228	22	637	22	634
QDM08619.1	6.29e-228	22	637	22	634
QRQ56347.1	7.48e-228	22	637	22	634
SCV08998.1	7.48e-228	22	637	22	634

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000561	0.953824	0.044794	0.000296	0.000261	0.000231

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000854_01650.