dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000000864_00205

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Basic Information help

Species

CAG-632 sp900539185

Lineage

Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; CAG-632; CAG-632 sp900539185

CAZyme ID

MGYG000000864_00205

CAZy Family

GH25

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
576		61755.79	4.5397

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000864	2413963	MAG	United States	North America

Gene Location

Start: 212990; End: 214720 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000000864_00205.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH25	193	379	4.5e-45	0.9943502824858758

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd06414	GH25_LytC-like	6.79e-80	192	389	3	191	The LytC lysozyme of Streptococcus pneumoniae is a bacterial cell wall hydrolase that cleaves the beta1-4-glycosydic bond located between the N-acetylmuramoyl-N-glucosaminyl residues of the cell wall polysaccharide chains. LytC is composed of a C-terminal glycosyl hydrolase family 25 (GH25) domain and an N-terminal choline-binding module (CBM) consisting of eleven homologous repeats that specifically recognizes the choline residues of pneumococcal lipoteichoic and teichoic acids. This domain arrangement is the reverse of the major pneumococcal autolysin, LytA, and the CPL-1-like lytic enzymes of the pneumococcal bacteriophages, in which the CBM (consisting of six repeats) is at the C-terminus. This model represents the C-terminal catalytic domain of the LytC-like enzymes.
cd00599	GH25_muramidase	1.85e-37	192	387	2	185	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues. This family of muramidases contains a glycosyl hydrolase family 25 (GH25) catalytic domain and is found in bacteria, fungi, slime molds, round worms, protozoans and bacteriophages. The bacteriophage members are referred to as endolysins which are involved in lysing the host cell at the end of the replication cycle to allow release of mature phage particles. Endolysins are typically modular enzymes consisting of a catalytically active domain that hydrolyzes the peptidoglycan cell wall and a cell wall-binding domain that anchors the protein to the cell wall. Endolysins generally have narrow substrate specificities with either intra-species or intra-genus bacteriolytic activity.
NF033483	PknB_PASTA_kin	3.23e-35	400	535	427	563	Stk1 family PASTA domain-containing Ser/Thr kinase.
NF033483	PknB_PASTA_kin	6.27e-35	398	539	356	499	Stk1 family PASTA domain-containing Ser/Thr kinase.
pfam01183	Glyco_hydro_25	3.54e-32	193	379	1	180	Glycosyl hydrolases family 25.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ADL33290.1	4.70e-53	150	389	989	1225
BCK81546.1	4.78e-53	150	389	226	472
AVM48757.1	2.42e-49	174	389	4	214
QHI72152.1	6.24e-48	192	392	95	291
ADK67502.1	1.91e-47	173	387	169	378

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2WW5_A	2.29e-17	175	389	250	468	3D-structureof the modular autolysin LytC from Streptococcus pneumoniae at 1.6 A resolution [Streptococcus pneumoniae R6],2WWD_A 3D-structure of the modular autolysin LytC from Streptococcus pneumoniae in complex with pneummococcal peptidoglycan fragment [Streptococcus pneumoniae R6]
2WWC_A	5.41e-17	175	389	250	468	3D-structureof the modular autolysin LytC from Streptococcus pneumoniae in complex with synthetic peptidoglycan ligand [Streptococcus pneumoniae R6]
1JFX_A	1.47e-16	192	386	7	200	Crystalstructure of the bacterial lysozyme from Streptomyces coelicolor at 1.65 A resolution [Streptomyces coelicolor]
4KRU_A	7.95e-14	192	386	22	205	X-raystructure of catalytic domain of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101]
4KRT_A	3.54e-13	192	386	22	205	X-raystructure of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101],4KRT_B X-ray structure of endolysin from clostridium perfringens phage phiSM101 [Clostridium phage phiSM101]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P25310	2.91e-15	192	386	84	277	Lysozyme M1 OS=Streptomyces globisporus OX=1908 GN=acm PE=1 SV=1
Q8FUI5	5.03e-12	398	538	372	514	Probable serine/threonine-protein kinase CE0033 OS=Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395) OX=196164 GN=CE0033 PE=3 SV=1
Q8R9T6	5.46e-10	409	535	417	544	Probable serine/threonine-protein kinase Sps1 OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=sps1 PE=3 SV=1
Q8G4G1	8.06e-10	409	498	621	711	Probable serine/threonine-protein kinase pknA2 OS=Bifidobacterium longum (strain NCC 2705) OX=206672 GN=pknA2 PE=3 SV=1
Q9KIG4	9.67e-10	406	538	445	578	Serine/threonine-protein kinase PK-1 OS=Streptomyces toyocaensis OX=55952 GN=spk1 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.936462	0.028160	0.001930	0.000225	0.000136	0.033121

TMHMM Annotations download full data without filtering help

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12	34