You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000870_00519
You are here: Home > Sequence: MGYG000000870_00519
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Akkermansia sp004167605 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales; Akkermansiaceae; Akkermansia; Akkermansia sp004167605 | |||||||||||
| CAZyme ID | MGYG000000870_00519 | |||||||||||
| CAZy Family | GH18 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 138888; End: 140330 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH18 | 181 | 459 | 9.8e-41 | 0.9391891891891891 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00704 | Glyco_hydro_18 | 3.85e-41 | 181 | 457 | 1 | 307 | Glycosyl hydrolases family 18. |
| cd06548 | GH18_chitinase | 1.26e-37 | 262 | 457 | 102 | 322 | The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. |
| smart00636 | Glyco_18 | 2.45e-34 | 207 | 457 | 26 | 334 | Glyco_18 domain. |
| cd00598 | GH18_chitinase-like | 1.23e-31 | 182 | 457 | 1 | 210 | The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods. Chitinases have been identified in viruses, bacteria, fungi, protozoan parasites, insects, and plants. The structure of the GH18 domain is an eight-stranded beta/alpha barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel. The GH18 family includes chitotriosidase, chitobiase, hevamine, zymocin-alpha, narbonin, SI-CLP (stabilin-1 interacting chitinase-like protein), IDGF (imaginal disc growth factor), CFLE (cortical fragment-lytic enzyme) spore hydrolase, the type III and type V plant chitinases, the endo-beta-N-acetylglucosaminidases, and the chitolectins. The GH85 (glycosyl hydrolase, family 85) ENGases (endo-beta-N-acetylglucosaminidases) are closely related to the GH18 chitinases and are included in this alignment model. |
| cd06545 | GH18_3CO4_chitinase | 2.73e-29 | 218 | 457 | 34 | 242 | The Bacteroides thetaiotaomicron protein represented by pdb structure 3CO4 is an uncharacterized bacterial member of the family 18 glycosyl hydrolases with homologs found in Flavobacterium, Stigmatella, and Pseudomonas. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QWP70637.1 | 0.0 | 1 | 480 | 1 | 480 |
| QWO91390.1 | 0.0 | 1 | 480 | 1 | 480 |
| QWO85994.1 | 0.0 | 1 | 480 | 1 | 480 |
| QWO95829.1 | 0.0 | 1 | 480 | 1 | 480 |
| QWO93300.1 | 0.0 | 1 | 480 | 1 | 480 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3CO4_A | 3.58e-19 | 237 | 452 | 53 | 279 | Crystalstructure of a chitinase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],3FND_A Crystal structure of a chitinase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron] |
| 5Y29_A | 2.49e-18 | 266 | 457 | 100 | 351 | Crystalstructure of Ostrinia furnacalis Group II chitinase catalytic domain 1 [Ostrinia furnacalis],5Y2B_A Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with HEPTA-N-ACETYLCHITOOCTAOSE (NAG)7 [Ostrinia furnacalis] |
| 6JAV_A | 2.77e-18 | 266 | 457 | 100 | 351 | Crystalstructure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a piperidine-thienopyridine derivative [Ostrinia furnacalis],6JAW_A Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a napthalimide derivative [Ostrinia furnacalis],6JAX_A Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with chitooctaose [(GlcN)8] [Ostrinia furnacalis],6JAY_A Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a dipyrido-pyrimidine derivative [Ostrinia furnacalis] |
| 6XYZ_A | 1.16e-17 | 197 | 452 | 29 | 285 | Crystalstructure of the GH18 chitinase ChiB from the chitin utilization locus of Flavobacterium johnsoniae [Flavobacterium johnsoniae UW101] |
| 3WD0_A | 1.59e-14 | 251 | 459 | 107 | 419 | Serratiamarcescens Chitinase B, tetragonal form [Serratia marcescens],3WD1_A Serratia marcescens Chitinase B complexed with syn-triazole inhibitor [Serratia marcescens],3WD2_A Serratia marcescens Chitinase B complexed with azide inhibitor [Serratia marcescens],3WD3_A Serratia marcescens Chitinase B complexed with azide inhibitor [Serratia marcescens],3WD4_A Serratia marcescens Chitinase B complexed with azide inhibitor and quinoline compound [Serratia marcescens],4Z2G_A Serratia marcescens Chitinase B complexed with macrolide inhibitor 26 [Serratia marcescens],4Z2H_A Serratia marcescens Chitinase B complexed with macrolide inhibitor 29 [Serratia marcescens],4Z2I_A Serratia marcescens Chitinase B complexed with macrolide inhibitor 30 [Serratia marcescens],4Z2J_A Serratia marcescens Chitinase B complexed with macrolide inhibitor 31 [Serratia marcescens],4Z2K_A Serratia marcescens Chitinase B complexed with macrolide inhibitor 32 [Serratia marcescens],4Z2L_A Serratia marcescens Chitinase B complexed with macrolide inhibitor 33 [Serratia marcescens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q92222 | 1.01e-14 | 267 | 457 | 111 | 347 | Endochitinase B OS=Emericella nidulans OX=162425 GN=chiB PE=1 SV=3 |
| G5EAZ3 | 1.01e-14 | 267 | 457 | 111 | 347 | Endochitinase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=chiB PE=1 SV=1 |
| Q9W5U2 | 7.60e-14 | 263 | 457 | 1999 | 2253 | Probable chitinase 10 OS=Drosophila melanogaster OX=7227 GN=Cht10 PE=2 SV=2 |
| P11797 | 8.63e-14 | 251 | 459 | 103 | 415 | Chitinase B OS=Serratia marcescens OX=615 GN=chiB PE=1 SV=1 |
| E9QRF2 | 1.22e-13 | 270 | 476 | 153 | 412 | Endochitinase B1 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=chiB1 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.009036 | 0.865613 | 0.124401 | 0.000401 | 0.000252 | 0.000249 |