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CAZyme Information: MGYG000000939_00170
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS1241 sp900540495 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-138; UMGS1241; UMGS1241 sp900540495 | |||||||||||
| CAZyme ID | MGYG000000939_00170 | |||||||||||
| CAZy Family | GT83 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 188667; End: 192539 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 865 | 1088 | 3.2e-54 | 0.9237668161434978 |
| GT83 | 304 | 717 | 4e-16 | 0.7296296296296296 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 4.24e-23 | 1108 | 1262 | 3 | 172 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG5542 | COG5542 | 6.25e-17 | 288 | 448 | 78 | 230 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG1928 | PMT1 | 7.73e-17 | 1111 | 1271 | 504 | 680 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam13231 | PMT_2 | 1.15e-14 | 893 | 1037 | 1 | 136 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
| pfam02366 | PMT | 2.35e-13 | 864 | 1034 | 16 | 195 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BCG57259.1 | 5.23e-236 | 7 | 1270 | 12 | 1257 |
| QUL55595.1 | 3.22e-235 | 26 | 1270 | 27 | 1261 |
| AIQ56104.1 | 9.21e-235 | 26 | 1270 | 27 | 1262 |
| CQR52353.1 | 3.22e-234 | 26 | 1278 | 27 | 1266 |
| BBI34061.1 | 2.00e-233 | 7 | 1283 | 17 | 1238 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 1.56e-33 | 871 | 1270 | 73 | 507 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 1.56e-33 | 871 | 1270 | 73 | 507 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 2.91e-30 | 871 | 1270 | 67 | 501 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| Q8NRZ6 | 5.22e-14 | 894 | 1230 | 99 | 459 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000238 | 0.998985 | 0.000226 | 0.000169 | 0.000170 | 0.000155 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 215 | 237 |
| 250 | 272 |
| 282 | 304 |
| 309 | 326 |
| 331 | 353 |
| 365 | 387 |
| 397 | 419 |
| 426 | 445 |
| 450 | 472 |
| 491 | 513 |
| 528 | 547 |
| 568 | 587 |
| 592 | 606 |
| 613 | 635 |
| 650 | 667 |
| 719 | 741 |
| 913 | 935 |
| 969 | 991 |
| 1011 | 1033 |
| 1062 | 1084 |
| 1158 | 1180 |
| 1192 | 1209 |
| 1214 | 1233 |
| 1246 | 1268 |