CAZyme Information: MGYG000000945_00515

Basic Information

• Species: CAG-245 sp900552135
• Lineage: Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-245; CAG-245 sp900552135
• CAZyme ID: MGYG000000945_00515
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
286	MGYG000000945_4|CGC1	33523.33	9.2847

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000945	1468207	MAG	United Kingdom	Europe

• Gene Location: Start: 41887; End: 42747 Strand: -

Full Sequence      

MTIDIICPLYNAEKYIENQYNQIKSQGFYNNVKNINYIITESKDGTLSVVERLQKKDEKI
KYNVIKKQEFSHSLSREEVAKNSTADILVFITQDVKIERDDWLEKLATPIANGEVEACYS
RQLCENSTIERYTRECNYPSQSVIKSKDDIEKLGLNTFFFSDASSAIKTDIFKNLNGYDG
KDFPTNEDMYIAYKLITNGYKIKYCADSEVVHSHKFTLKQQYKRYYDTGKFFKQNEYLNK
YKVNKSGGKLAVYVLKRAWQEKNWKVLFNFIPNMMARFIGMKVGKM

Enzyme Prediction     

No EC number prediction in MGYG000000945_00515.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	4	174	6.2e-16	0.9823529411764705

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd02525	Succinoglycan_BP_ExoA	1.28e-14	2	231	1	226	ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.
cd00761	Glyco_tranf_GTA_type	6.12e-12	5	202	1	154	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
pfam00535	Glycos_transf_2	1.86e-10	4	172	1	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
COG1215	BcsA	1.11e-07	2	211	55	263	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd04196	GT_2_like_d	1.25e-06	4	121	1	116	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ACR73462.1	5.24e-106	1	285	1	279
AWZ49463.1	7.96e-106	1	285	1	279
BAM95104.1	3.22e-105	1	284	5	281
AJF30794.1	8.88e-105	1	285	1	281
AJF33857.1	8.88e-105	1	285	1	281

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P26403	2.21e-34	1	285	1	282	O antigen biosynthesis rhamnosyltransferase RfbN OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfbN PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000063	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000000945_00515.