You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000959_01590
You are here: Home > Sequence: MGYG000000959_01590
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Ruminococcus sp900752785 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus; Ruminococcus sp900752785 | |||||||||||
| CAZyme ID | MGYG000000959_01590 | |||||||||||
| CAZy Family | CBM4 | |||||||||||
| CAZyme Description | Cellulose 1,4-beta-cellobiosidase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 7477; End: 10536 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH9 | 353 | 922 | 8.3e-99 | 0.9880382775119617 |
| CBM4 | 37 | 179 | 3.4e-21 | 0.9603174603174603 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00759 | Glyco_hydro_9 | 7.61e-53 | 353 | 922 | 1 | 374 | Glycosyl hydrolase family 9. |
| cd02850 | E_set_Cellulase_N | 2.01e-26 | 244 | 342 | 2 | 86 | N-terminal Early set domain associated with the catalytic domain of cellulase. E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others. |
| pfam02927 | CelD_N | 1.85e-23 | 244 | 332 | 3 | 80 | Cellulase N-terminal ig-like domain. |
| pfam02018 | CBM_4_9 | 2.80e-07 | 41 | 179 | 8 | 129 | Carbohydrate binding domain. This family includes diverse carbohydrate binding domains. |
| cd14256 | Dockerin_I | 3.30e-07 | 950 | 1008 | 2 | 57 | Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CBL17684.1 | 1.39e-242 | 1 | 987 | 2 | 932 |
| CAS03458.1 | 1.88e-224 | 1 | 930 | 1 | 907 |
| ADU22927.1 | 1.64e-223 | 3 | 932 | 6 | 905 |
| AAR01216.1 | 5.19e-223 | 13 | 930 | 8 | 903 |
| BAJ05815.1 | 7.21e-222 | 3 | 932 | 6 | 905 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UT9_A | 2.39e-125 | 244 | 925 | 7 | 604 | ChainA, CELLULOSE 1,4-BETA-CELLOBIOSIDASE [Acetivibrio thermocellus] |
| 1RQ5_A | 2.46e-125 | 244 | 930 | 7 | 609 | ChainA, Cellobiohydrolase [Acetivibrio thermocellus] |
| 3X17_A | 5.36e-56 | 244 | 923 | 18 | 554 | Crystalstructure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium],3X17_B Crystal structure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium] |
| 6DHT_A | 6.52e-56 | 244 | 925 | 18 | 564 | Bacteroidesovatus GH9 Bacova_02649 [Bacteroides ovatus ATCC 8483] |
| 5U0H_A | 8.37e-47 | 283 | 931 | 20 | 546 | Crystalstructure of GH family 9 endoglucanase J30 [Thermobacillus composti KWC4] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P0C2S1 | 1.11e-136 | 36 | 966 | 42 | 849 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus OX=1515 GN=celK PE=1 SV=1 |
| A3DCH1 | 2.17e-136 | 36 | 966 | 42 | 849 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celK PE=3 SV=1 |
| Q05156 | 5.04e-108 | 41 | 928 | 39 | 745 | Cellulase 1 OS=Streptomyces reticuli OX=1926 GN=cel1 PE=1 SV=1 |
| P10476 | 4.63e-96 | 230 | 929 | 23 | 602 | Endoglucanase A OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=celA PE=3 SV=2 |
| P14090 | 3.21e-95 | 244 | 937 | 341 | 918 | Endoglucanase C OS=Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) OX=590998 GN=cenC PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000475 | 0.998681 | 0.000181 | 0.000277 | 0.000189 | 0.000165 |
