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CAZyme Information: MGYG000000963_00764

You are here: Home > Sequence: MGYG000000963_00764

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-617 sp900553285
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; CAG-617; CAG-617 sp900553285
CAZyme ID MGYG000000963_00764
CAZy Family GT9
CAZyme Description Lipopolysaccharide core heptosyltransferase RfaQ
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
348 39921.85 9.3622
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000963 1599597 MAG Denmark Europe
Gene Location Start: 7839;  End: 8885  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000963_00764.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 71 312 1.8e-33 0.92

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03789 GT9_LPS_heptosyltransferase 2.04e-48 4 337 1 275
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0859 RfaF 2.29e-47 3 337 2 326
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
PRK10422 PRK10422 2.18e-17 3 341 6 343
lipopolysaccharide core biosynthesis protein; Provisional
pfam01075 Glyco_transf_9 6.36e-14 70 287 1 211
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
PRK10916 PRK10916 1.30e-08 4 287 2 289
ADP-heptose--LPS heptosyltransferase RfaF.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AVV52897.1 1.21e-121 6 345 13 353
AOH41188.1 1.21e-121 6 345 13 353
QIK54674.1 4.77e-119 4 345 3 348
QIK60100.1 1.56e-117 4 345 3 348
BAR51520.1 4.26e-116 2 347 7 353

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3TOV_A 2.46e-06 3 296 9 297
Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9R9D5 9.47e-14 14 341 5 331
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1
P25742 2.40e-13 14 335 5 325
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000057 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000963_00764.