CAZyme Information: MGYG000000967_01219

Basic Information

• Species: UMGS1441 sp900543365
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; CAG-274; UMGS1441; UMGS1441 sp900543365
• CAZyme ID: MGYG000000967_01219
• CAZy Family: PL9
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1315		144246.92	4.8111

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000000967	1698990	MAG	Spain	Europe

• Gene Location: Start: 553; End: 4500 Strand: -

Full Sequence      

MKKRIIYAGMALTMAFSSVGSIPALGAIDSSWIVDWTGKDGDINYNVTSTADNKVVMENT
KVNNGKLSDSEDSIIYYAKELENSEDFEISAKVTINEYNTMSESSNPQQGSVGIAVLDSL
YHKTDDITYDDGIFLGTYAKDKKSDMAFTALYRNASNKKTIGDTLSDSIKNTGSNLGTYA
LSIKKEGNAYTLTCGDKSQVIEMTSFEDTIYPCLYIARNVKATFSDVKITKPTKKAVSME
IKGECKTKYIYGEELDLTGIDVIVTYNDLSKASVKDYLVKDYNPKKVGKQKVTLVKGDAT
ATIDVEVSNLEVKSINTDFMPVKTSYAKGDVFKTEGLQVSADYSNGTTEILSPDKYILKI
DGKTVKDGDKLTAMGKKQVKVYRADEAGYSSKVVGTFYININKNPINSITLTEPKKKVYY
LGDSLDTSGMSVTSTFVDNNNKEIKEVLKPCDYEVTGFSSDTEGDKIITVTSVANPEVKA
TFKVNVFKRQAQKIQVTDYPRTTYAVGENFDSKDMVVSIVYDNGDIEPTDSYTLDTSAFN
SSAVGKTSVTVNADGFESITLPVTIVSELNNQWRASTFGQSSSFGVAEGVTGVKAENYGT
VQGKINVSAWNGAGKITQDHDGMTYYYTQIKGDSGFKISADITVDKFLEHDNDDTKRSGQ
ESFGIMARDVVPLTAADGTLTIDPTTAKVDADGVVVPMDTDKLFASNMTILGGYSGMAWP
SDKSDASYDKKTKLNRINLMVREGVTAIDGGGKRIGPFAVSSDFPKEGNKYRITLERVNG
GLVAKCYNYQTEESMEYTYADDSFLTVQNKDYAYVGFFAARWAQITVENVEFYETDKSTS
KTITVADLDDAKTPSFTFEQSPYSTNPVYDFDLHLSKASGTVTVKMNDKVVAQDVPVKGT
THFQANLRPNSLNKLVAVFTPDDSLNLTSYEPIVIRENIYHRSVNSAVTTVFASPNGTYK
GDGTENNPYDIYTAIGFLQPGQTLELLGGTYKLDKPIEILYGNNGTANKMKTVEAYKGAK
VVFDGQRESANMLMNGDYWKFKGIEFTRSANNQKGAHLGGSHNIIENCIFSNNGDTGLQI
SRIDEDKQDTFDKWPSYNLILNCESYNNCDPSMINADGFGAKLTVGVGNVFRNCKSHNNL
DDGWDLYTKVNTGAIGPVTLENCETYRNGYKLNDDGTETPYNAGGNNGFKCGGENVPVQH
ILIDCKSWGNKACGLTTNFNPTLKLVNVACYDNEKSNFYLYSDYPENYNYDVQGVYSANG
GEADYIGTVTHSTEYKNANKTPLVSEINYWSKDKGQIGVNSLGEAPSKAVADKLK

Enzyme Prediction     

EC	4.2.2.2

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
PL9	949	1289	6.8e-105	0.8986666666666666

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07523	Big_3	2.25e-04	499	565	2	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
cd14251	PL-6	8.16e-04	973	1103	9	133	Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate.
pfam07523	Big_3	0.002	246	307	4	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
pfam07523	Big_3	0.002	413	486	1	67	Bacterial Ig-like domain (group 3). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.
pfam14592	Chondroitinas_B	0.005	966	1070	2	107	Chondroitinase B. This family includes chondroitinases. These enzymes cleave the glycosaminoglycan dermatan sulfate.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BAC87940.1	1.09e-214	63	1264	70	1193
AGI38277.1	1.53e-214	63	1264	70	1193
AGC67199.1	1.53e-214	63	1264	70	1193
ANW97669.1	1.53e-214	63	1264	70	1193
ANX00231.1	2.15e-214	63	1264	70	1193

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1RU4_A	5.27e-32	952	1233	18	292	ChainA, Pectate lyase [Dickeya chrysanthemi]
5OLQ_A	4.45e-09	1096	1201	168	275	Rhamnogalacturonanlyase [Bacteroides thetaiotaomicron],5OLQ_B Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLQ_C Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLR_A Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLR_B Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLR_C Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron],5OLS_A Rhamnogalacturonan lyase [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P22751	4.78e-66	573	1259	34	663	Pectate disaccharide-lyase OS=Dickeya chrysanthemi OX=556 GN=pelX PE=1 SV=1
P0C1A6	5.55e-32	952	1233	43	317	Pectate lyase L OS=Dickeya chrysanthemi OX=556 GN=pelL PE=3 SV=1
P0C1A7	4.47e-31	952	1233	43	317	Pectate lyase L OS=Dickeya dadantii (strain 3937) OX=198628 GN=pelL PE=1 SV=1
A0A401ETL2	1.00e-06	319	486	1301	1451	Exo-beta-1,6-galactobiohydrolase OS=Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) OX=565042 GN=bl1,6Gal PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000277	0.999101	0.000155	0.000170	0.000147	0.000136

TMHMM  Annotations     

start	end
5	27