You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000977_00398
You are here: Home > Sequence: MGYG000000977_00398
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Clostridium sp900539375 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium sp900539375 | |||||||||||
| CAZyme ID | MGYG000000977_00398 | |||||||||||
| CAZy Family | GH13 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 12681; End: 16274 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH13 | 51 | 295 | 7.1e-64 | 0.9022556390977443 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11315 | AmyAc_bac1_AmyA | 4.03e-86 | 41 | 374 | 1 | 352 | Alpha amylase catalytic domain found in bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase). AmyA (EC 3.2.1.1) catalyzes the hydrolysis of alpha-(1,4) glycosidic linkages of glycogen, starch, related polysaccharides, and some oligosaccharides. This group includes Firmicutes, Proteobacteria, Actinobacteria, and Cyanobacteria. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase. |
| PRK14081 | PRK14081 | 1.97e-35 | 651 | 1090 | 5 | 458 | triple tyrosine motif-containing protein; Provisional |
| PRK14081 | PRK14081 | 8.43e-28 | 563 | 1066 | 9 | 625 | triple tyrosine motif-containing protein; Provisional |
| PRK14081 | PRK14081 | 1.05e-27 | 769 | 1184 | 29 | 460 | triple tyrosine motif-containing protein; Provisional |
| PRK14081 | PRK14081 | 2.85e-27 | 858 | 1195 | 30 | 373 | triple tyrosine motif-containing protein; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QES71965.1 | 1.93e-111 | 38 | 632 | 48 | 651 |
| AVK49730.1 | 2.68e-111 | 38 | 632 | 48 | 651 |
| AQS03274.1 | 9.98e-111 | 38 | 632 | 48 | 651 |
| AJG97367.1 | 2.60e-110 | 38 | 632 | 48 | 650 |
| CUU45913.1 | 5.17e-110 | 38 | 632 | 48 | 651 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1BAG_A | 1.78e-55 | 38 | 445 | 5 | 425 | ChainA, ALPHA-1,4-GLUCAN-4-GLUCANOHYDROLASE [Bacillus subtilis] |
| 3DC0_A | 3.04e-55 | 38 | 445 | 2 | 422 | Crystalstructure of native alpha-amylase from Bacillus sp. KR-8104 [Bacillus sp. KR-8104] |
| 1UA7_A | 5.60e-55 | 38 | 445 | 2 | 422 | ChainA, Alpha-amylase [Bacillus subtilis] |
| 1KXH_A | 8.34e-10 | 66 | 218 | 28 | 182 | ChainA, alpha-amylase [Pseudoalteromonas haloplanktis] |
| 1G94_A | 3.36e-09 | 66 | 218 | 28 | 182 | CRYSTALSTRUCTURE ANALYSIS OF THE TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA AMYLASE FROM PSEUDOALTEROMONAS HALOPLANCTIS IN COMPLEX WITH A HEPTA-SACCHARIDE AND A TRIS MOLECULE [Pseudoalteromonas haloplanktis],1G9H_A TERNARY COMPLEX BETWEEN PSYCHROPHILIC ALPHA-AMYLASE, COMII (PSEUDO TRI-SACCHARIDE FROM BAYER) AND TRIS (2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL) [Pseudoalteromonas haloplanktis],1L0P_A Crystal Structure Analysis Of The Complex Between Psychrophilic Alpha Amylase From Pseudoalteromonas Haloplanctis And Nitrate [Pseudoalteromonas haloplanktis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P23671 | 2.74e-103 | 37 | 445 | 49 | 463 | Alpha-amylase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) OX=272562 GN=amyA PE=3 SV=2 |
| P00691 | 7.93e-53 | 38 | 447 | 46 | 468 | Alpha-amylase OS=Bacillus subtilis (strain 168) OX=224308 GN=amyE PE=1 SV=2 |
| P30269 | 6.62e-33 | 34 | 457 | 140 | 625 | Alpha-amylase OS=Butyrivibrio fibrisolvens OX=831 GN=amyA PE=3 SV=1 |
| P29750 | 2.82e-12 | 66 | 215 | 65 | 224 | Alpha-amylase OS=Thermomonospora curvata OX=2020 GN=tam PE=1 SV=1 |
| O76284 | 2.00e-11 | 66 | 241 | 56 | 227 | Alpha-amylase-related protein OS=Drosophila bocqueti OX=74549 GN=Amyrel PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.001014 | 0.996281 | 0.002124 | 0.000199 | 0.000176 | 0.000176 |
