CAZyme Information: MGYG000001012_00863

Basic Information

• Species: Porphyromonas sp900539155
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae; Porphyromonas; Porphyromonas sp900539155
• CAZyme ID: MGYG000001012_00863
• CAZy Family: GT19
• CAZyme Description: Lipid-A-disaccharide synthase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
385	MGYG000001012_16|CGC1	42878.53	8.2298

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001012	2045709	MAG	Bangladesh	Asia

• Gene Location: Start: 8110; End: 9267 Strand: +

Full Sequence      

MKYLLIAGEASGDEHGARLIAELRKVDSAATFAFIGGDKMALQAGVAPLYHYREIAVMGF
TAVLRTLRKIRLAARLLQEEMRSNPPDVVIPIDYGGFNLRYTLPLAHRYGVPVVYYIPPK
VWASRRRRIKQLRRYTDICLTILPFEADYLSQRGVNARYVGNPSMASVGDLLASNAKLCD
TNRPYIALLPGSREAEIARNLPMMCQAIDLLPAPWRAVIAGAPSIDRAHYTPYLSERIEL
VTDKTLPLLAGSSAALVTSGTATLETALIGTPQVVAYRLPAGRLARWSFDHLLPISYFSL
VNLIAEHPVVEELLGDRMTPQRLVQALVPLLDRESVAYQAQQQQYHNIRQHLRGELVAAE
GAAEIIYHALTTQWEPDRWTGDVED

Enzyme Prediction     

No EC number prediction in MGYG000001012_00863.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT19	4	353	1.9e-98	0.9915254237288136

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK00025	lpxB	9.60e-87	1	366	2	371	lipid-A-disaccharide synthase; Reviewed
COG0763	LpxB	3.00e-81	1	366	2	375	Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis].
pfam02684	LpxB	1.38e-67	4	366	2	374	Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide.
TIGR00215	lpxB	3.61e-57	4	331	9	345	lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK14089	PRK14089	1.46e-41	1	326	2	312	lipid-A-disaccharide synthase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AEE12174.1	4.11e-227	1	377	1	377
SQH73726.1	3.13e-101	1	366	1	372
QUB42945.1	1.67e-99	1	373	1	374
ATS09476.1	8.01e-94	1	366	1	370
ATS02318.1	3.20e-93	1	366	1	370

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5W8N_A	7.88e-39	5	366	11	377	LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)]
5W8S_A	7.88e-39	5	366	11	377	LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q1D393	9.80e-61	2	370	6	378	Lipid-A-disaccharide synthase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxB PE=3 SV=1
Q6ALW0	5.66e-56	4	323	13	342	Lipid-A-disaccharide synthase OS=Desulfotalea psychrophila (strain LSv54 / DSM 12343) OX=177439 GN=lpxB PE=3 SV=1
B6J161	1.71e-55	4	370	7	374	Lipid-A-disaccharide synthase OS=Coxiella burnetii (strain CbuG_Q212) OX=434923 GN=lpxB PE=3 SV=1
A9KC41	2.40e-55	4	370	7	374	Lipid-A-disaccharide synthase OS=Coxiella burnetii (strain Dugway 5J108-111) OX=434922 GN=lpxB PE=3 SV=1
B6J9H1	2.40e-55	4	370	7	374	Lipid-A-disaccharide synthase OS=Coxiella burnetii (strain CbuK_Q154) OX=434924 GN=lpxB PE=3 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000066	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001012_00863.