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CAZyme Information: MGYG000001014_00454
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Varibaculum timonense | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Varibaculum; Varibaculum timonense | |||||||||||
| CAZyme ID | MGYG000001014_00454 | |||||||||||
| CAZy Family | GH35 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 20; End: 3814 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH35 | 8 | 235 | 6.6e-38 | 0.6482084690553745 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam01301 | Glyco_hydro_35 | 2.66e-31 | 9 | 236 | 108 | 315 | Glycosyl hydrolases family 35. |
| pfam13364 | BetaGal_dom4_5 | 2.49e-20 | 1023 | 1134 | 1 | 105 | Beta-galactosidase jelly roll domain. This domain is found in beta galactosidase enzymes. It has a jelly roll fold. |
| smart01029 | BetaGal_dom2 | 6.57e-20 | 568 | 746 | 1 | 182 | Beta-galactosidase, domain 2. This is the second domain of the five-domain beta-galactosidase enzyme that altogether catalyses the hydrolysis of beta(1-3) and beta(1-4) galactosyl bonds in oligosaccharides as well as the inverse reaction of enzymatic condensation and trans-glycosylation. This domain is made up of 16 antiparallel beta-strands and an alpha-helix at its C terminus. The fold of this domain appears to be unique. In addition, the last seven strands of the domain form a subdomain with an immunoglobulin-like (I-type Ig) fold in which the first strand is divided between the two beta-sheets. In penicillin spp this strand is interrupted by a 12-residue insertion which forms an additional edge-strand to the second beta-sheet of the sub-domain. The remainder of the second domain forms a series of beta-hairpins at its N terminus, four strands of which are contiguous with part of the Ig-like sub-domain, forming in total a seven-stranded antiparallel beta-sheet. This domain is associated with family Glyco_hydro_35, which is N-terminal to it, but itself has no metazoan members. |
| PLN03059 | PLN03059 | 2.11e-05 | 14 | 253 | 149 | 357 | beta-galactosidase; Provisional |
| pfam17996 | CE2_N | 0.001 | 354 | 435 | 18 | 92 | Carbohydrate esterase 2 N-terminal. This is the N-terminal beta-sheet domain with jelly roll topology found in CE2 acetyl-esterase from the bacterium Clostridium thermocellum. This enzyme displays dual activities, it catalyses the deacetylation of plant polysaccharides and also potentiates the activity of its appended cellulase catalytic module through its noncatalytic cellulose binding function. This N-terminal jelly-roll domain appears to extend the substrate/cellulose binding cleft of the catalytic domain in C.thermocellum. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AOZ72117.1 | 0.0 | 1 | 1177 | 178 | 1312 |
| VEG55570.1 | 0.0 | 1 | 1156 | 188 | 1330 |
| QQM67568.1 | 0.0 | 1 | 1169 | 187 | 1339 |
| QWW19060.1 | 0.0 | 9 | 1152 | 172 | 1303 |
| QGH69595.1 | 1.26e-272 | 17 | 1148 | 202 | 1319 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4IUG_A | 2.10e-47 | 546 | 1140 | 391 | 968 | Crystalstructure of beta-galactosidase from Aspergillus oryzae in complex with galactose [Aspergillus oryzae] |
| 1TG7_A | 6.51e-45 | 558 | 1138 | 364 | 932 | Nativestructure of beta-galactosidase from Penicillium sp. [Penicillium sp.],1XC6_A Native Structure Of Beta-Galactosidase from Penicillium sp. in complex with Galactose [Penicillium sp.] |
| 5IFP_A | 3.04e-44 | 615 | 1154 | 456 | 980 | StructureOf Beta-galactosidase From Aspergillus Niger [Aspergillus niger CBS 513.88] |
| 5IFT_A | 3.04e-44 | 615 | 1154 | 456 | 980 | STRUCTUREOF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 3-b-Galactopyranosyl glucose [Aspergillus niger CBS 513.88],5IHR_A Structure Of E298q-beta-galactosidase From Aspergillus Niger In Complex With Allolactose [Aspergillus niger CBS 513.88],5JUV_A STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-b-Galactopyranosyl galactose [Aspergillus niger CBS 513.88],5MGC_A STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 4-Galactosyl-lactose [Aspergillus niger CBS 513.88],5MGD_A STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 6-Galactosyl-lactose [Aspergillus niger CBS 513.88] |
| 3OG2_A | 7.60e-42 | 615 | 1139 | 436 | 965 | ChainA, Beta-galactosidase [Trichoderma reesei],3OGR_A Chain A, Beta-galactosidase [Trichoderma reesei],3OGS_A Chain A, Beta-galactosidase [Trichoderma reesei],3OGV_A Chain A, Beta-galactosidase [Trichoderma reesei] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| B8N6V7 | 1.52e-46 | 546 | 1140 | 391 | 968 | Probable beta-galactosidase A OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167) OX=332952 GN=lacA PE=3 SV=1 |
| Q2UCU3 | 1.52e-46 | 546 | 1140 | 391 | 968 | Beta-galactosidase A OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=lacA PE=1 SV=1 |
| Q700S9 | 4.11e-44 | 558 | 1138 | 404 | 972 | Beta-galactosidase A OS=Penicillium sp. OX=5081 GN=lacA PE=1 SV=1 |
| Q4ZHV7 | 5.36e-44 | 615 | 1154 | 456 | 980 | Probable beta-galactosidase A OS=Aspergillus phoenicis OX=5063 GN=lacA PE=2 SV=1 |
| A1D1Z9 | 7.06e-44 | 615 | 1140 | 456 | 969 | Probable beta-galactosidase A OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=lacA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000059 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
