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CAZyme Information: MGYG000001039_00819
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phocaeicola sp900553185 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900553185 | |||||||||||
| CAZyme ID | MGYG000001039_00819 | |||||||||||
| CAZy Family | GT27 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 32714; End: 34360 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT27 | 8 | 274 | 5.8e-35 | 0.888135593220339 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd02510 | pp-GalNAc-T | 1.43e-19 | 7 | 245 | 1 | 244 | pp-GalNAc-T initiates the formation of mucin-type O-linked glycans. UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferases (pp-GalNAc-T) initiate the formation of mucin-type, O-linked glycans by catalyzing the transfer of alpha-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to hydroxyl groups of Ser or Thr residues of core proteins to form the Tn antigen (GalNAc-a-1-O-Ser/Thr). These enzymes are type II membrane proteins with a GT-A type catalytic domain and a lectin domain located on the lumen side of the Golgi apparatus. In human, there are 15 isozymes of pp-GalNAc-Ts, representing the largest of all glycosyltransferase families. Each isozyme has unique but partially redundant substrate specificity for glycosylation sites on acceptor proteins. |
| pfam00535 | Glycos_transf_2 | 9.51e-16 | 7 | 119 | 1 | 115 | Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. |
| cd00761 | Glyco_tranf_GTA_type | 3.55e-14 | 8 | 130 | 1 | 126 | Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities. |
| COG0463 | WcaA | 3.51e-08 | 6 | 100 | 5 | 102 | Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]. |
| cd06423 | CESA_like | 1.65e-07 | 8 | 90 | 1 | 87 | CESA_like is the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QIK61404.1 | 8.04e-130 | 4 | 545 | 10 | 549 |
| QIU94695.1 | 5.72e-73 | 4 | 316 | 3 | 310 |
| QUB82074.1 | 2.48e-57 | 6 | 318 | 7 | 314 |
| ALZ75925.1 | 5.17e-45 | 4 | 311 | 2 | 297 |
| BAR48611.1 | 1.12e-29 | 3 | 145 | 8 | 148 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6S22_A | 1.06e-12 | 7 | 382 | 186 | 554 | Crystalstructure of the TgGalNAc-T3 in complex with UDP, manganese and FGF23c [Taeniopygia guttata],6S24_A Crystal structure of the TgGalNAc-T3 in complex with UDP, manganese and the peptide 3 [Taeniopygia guttata] |
| 6E7I_A | 4.60e-11 | 7 | 235 | 96 | 325 | HumanppGalNAcT2 I253A/L310A Mutant with EA2 and UDP [Homo sapiens] |
| 6NQT_A | 4.86e-11 | 7 | 235 | 139 | 368 | GalNac-T2soaked with UDP-sugar [Homo sapiens],6NQT_B GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_C GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_D GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_E GalNac-T2 soaked with UDP-sugar [Homo sapiens],6NQT_F GalNac-T2 soaked with UDP-sugar [Homo sapiens] |
| 2FFU_A | 1.00e-10 | 7 | 235 | 69 | 298 | CrystalStructure of Human ppGalNAcT-2 complexed with UDP and EA2 [Homo sapiens],2FFV_A Human ppGalNAcT-2 complexed with manganese and UDP [Homo sapiens],2FFV_B Human ppGalNAcT-2 complexed with manganese and UDP [Homo sapiens] |
| 6EGS_A | 1.00e-10 | 7 | 235 | 71 | 300 | Crystalstructure of the GalNAc-T2 F104S mutant in complex with UDP-GalNAc [Homo sapiens],6EGS_B Crystal structure of the GalNAc-T2 F104S mutant in complex with UDP-GalNAc [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q6WV19 | 1.16e-13 | 7 | 235 | 205 | 434 | Polypeptide N-acetylgalactosaminyltransferase 2 OS=Drosophila melanogaster OX=7227 GN=Pgant2 PE=1 SV=2 |
| Q14435 | 2.69e-13 | 7 | 394 | 188 | 568 | Polypeptide N-acetylgalactosaminyltransferase 3 OS=Homo sapiens OX=9606 GN=GALNT3 PE=1 SV=2 |
| P70419 | 2.52e-12 | 7 | 382 | 188 | 556 | Polypeptide N-acetylgalactosaminyltransferase 3 OS=Mus musculus OX=10090 GN=Galnt3 PE=1 SV=3 |
| Q8I136 | 3.87e-11 | 7 | 235 | 154 | 383 | Polypeptide N-acetylgalactosaminyltransferase 4 OS=Caenorhabditis elegans OX=6239 GN=gly-4 PE=2 SV=2 |
| Q8C7U7 | 2.84e-10 | 7 | 383 | 180 | 549 | Polypeptide N-acetylgalactosaminyltransferase 6 OS=Mus musculus OX=10090 GN=Galnt6 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000081 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |