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CAZyme Information: MGYG000001065_02063

You are here: Home > Sequence: MGYG000001065_02063

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Enterocloster sp900538485
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Enterocloster; Enterocloster sp900538485
CAZyme ID MGYG000001065_02063
CAZy Family PL21
CAZyme Description Heparin and heparin-sulfate lyase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
810 MGYG000001065_49|CGC1 90339.8 4.9763
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001065 3284441 MAG Sweden Europe
Gene Location Start: 76526;  End: 78958  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001065_02063.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL21 441 501 1.5e-23 0.8888888888888888

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam18675 HepII_C 1.97e-09 723 807 1 87
Heparinase II C-terminal domain. Heparinase II (HepII) is an 85-kDa dimeric enzyme that depolymerizes both heparin and heparan sulfate glycosaminoglycans. The protein is composed of three domains: an N-terminal alpha-helical domain, a central two-layered beta-sheet domain, and a C-terminal domain forming a two-layered beta-sheet. The C-terminal domain contains nine beta-strands packed together in a manner resembling a beta-barrel.
pfam07940 Hepar_II_III 2.16e-04 441 497 29 85
Heparinase II/III-like protein. This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II and heparinase III. The former is known to degrade heparin and heparin sulphate, whereas the latter predominantly degrades heparin sulphate. Both are secreted into the periplasmic space upon induction with heparin.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCI63941.1 7.22e-166 68 808 42 791
BCI63940.1 1.40e-150 68 802 46 787
BBH20141.1 1.80e-126 54 807 221 958
ACN29695.1 5.23e-125 69 806 46 771
QUT43394.1 1.24e-124 69 806 45 778

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2FUQ_A 7.82e-120 69 806 23 745
ChainA, heparinase II protein [Pedobacter heparinus],2FUQ_B Chain B, heparinase II protein [Pedobacter heparinus]
3E80_A 8.24e-120 69 806 25 747
Structureof Heparinase II complexed with heparan sulfate degradation disaccharide product [Pedobacter heparinus],3E80_B Structure of Heparinase II complexed with heparan sulfate degradation disaccharide product [Pedobacter heparinus],3E80_C Structure of Heparinase II complexed with heparan sulfate degradation disaccharide product [Pedobacter heparinus]
3E7J_A 5.05e-117 69 806 25 747
ChainA, Heparinase II protein [Pedobacter heparinus],3E7J_B Chain B, Heparinase II protein [Pedobacter heparinus]
2FUT_A 2.98e-114 69 806 24 746
ChainA, heparinase II protein [Pedobacter heparinus],2FUT_B Chain B, heparinase II protein [Pedobacter heparinus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
C6XZB6 8.17e-119 69 806 48 770
Heparin and heparin-sulfate lyase OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=hepB PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000478 0.998513 0.000383 0.000212 0.000193 0.000175

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001065_02063.