CAZyme Information: MGYG000001078_00335

Basic Information

• Species: Rothia sp001808955
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Micrococcaceae; Rothia; Rothia sp001808955
• CAZyme ID: MGYG000001078_00335
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
378		42274.56	5.4929

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001078	1984981	MAG	Sweden	Europe

• Gene Location: Start: 376; End: 1512 Strand: +

Full Sequence      

MVEFLGWHAPTHPRLIVVMSSPTVAILVRTKDRPRFLSRTLENIAQQTFTDYTVCVINDG
GDEQATRAVIEASPLGLLGSNAHDSSRVQLLTTAGGNMEAASNAGLAATTSEYVAIHDDD
DLWAPEFLERTVAALEENGALMCTTRIVERYERENADGEFEVYEERIFHDGLPGMGLQFI
FRTNRAVPIGILYRRSLHELVGFYDESLPVVGDWEFNMRAASVADILLVDEPLAYWSLRP
DAEGAEANSVKRQADHARFDSMVRARAIREDLQAGARPGAYLYQAHLAADLERRVIDGHN
LTRESLDILRSIESRLERIEARQQSIENRQQAIEERLRVLKHLRTPGRALRSLAKRSLSQ
RSLVRRGAEDGSTGEKGA

Enzyme Prediction     

No EC number prediction in MGYG000001078_00335.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	26	154	1.6e-18	0.7176470588235294

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd00761	Glyco_tranf_GTA_type	2.43e-17	26	182	1	152	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.
pfam00535	Glycos_transf_2	2.26e-15	26	198	2	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd06433	GT_2_WfgS_like	7.90e-15	35	238	11	195	WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1215	BcsA	3.50e-13	22	207	54	235	Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility].
cd04196	GT_2_like_d	8.21e-11	25	236	1	202	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BAS20146.1	2.12e-222	5	378	1	366
BAI64008.1	2.55e-218	5	355	1	336
QXW97813.1	1.53e-207	19	355	1	334
VEI22149.1	4.49e-113	21	314	2	285
QXW92566.1	4.49e-113	21	314	2	285

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P39614	1.23e-12	24	221	3	183	Uncharacterized glycosyltransferase YwdF OS=Bacillus subtilis (strain 168) OX=224308 GN=ywdF PE=3 SV=1
P22639	2.56e-07	24	136	3	107	Uncharacterized glycosyltransferase alr2836 OS=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) OX=103690 GN=alr2836 PE=3 SV=2
D4GYH2	9.67e-06	22	222	7	192	Glycosyltransferase AglI OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) OX=309800 GN=aglI PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000079	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001078_00335.