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CAZyme Information: MGYG000001101_01825
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | HGM11523 sp900756545 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Monoglobales_A; UBA1381; HGM11523; HGM11523 sp900756545 | |||||||||||
| CAZyme ID | MGYG000001101_01825 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 21771; End: 24860 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 611 | 838 | 1.7e-55 | 0.9147982062780269 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 3.38e-26 | 850 | 1022 | 4 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG5542 | COG5542 | 6.78e-21 | 67 | 428 | 71 | 418 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG1928 | PMT1 | 1.66e-17 | 832 | 1028 | 484 | 696 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 4.05e-13 | 609 | 782 | 17 | 204 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG1807 | ArnT | 9.62e-12 | 627 | 1029 | 53 | 401 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BCN30459.1 | 2.37e-295 | 39 | 1029 | 41 | 1060 |
| QNM01664.1 | 4.04e-284 | 29 | 1029 | 22 | 1087 |
| BBF42044.1 | 3.28e-253 | 134 | 1028 | 2 | 921 |
| AIQ50579.1 | 1.05e-221 | 37 | 1026 | 4 | 1024 |
| QSF45552.1 | 7.24e-221 | 37 | 1026 | 252 | 1272 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| L8F4Z2 | 6.41e-31 | 615 | 1022 | 67 | 513 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| Q8NRZ6 | 3.98e-29 | 637 | 1022 | 98 | 517 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
| P9WN04 | 9.73e-29 | 615 | 1022 | 73 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 9.73e-29 | 615 | 1022 | 73 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000015 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 4 | 23 |
| 36 | 58 |
| 114 | 136 |
| 143 | 162 |
| 166 | 188 |
| 195 | 217 |
| 237 | 259 |
| 266 | 284 |
| 294 | 316 |
| 323 | 337 |
| 341 | 360 |
| 367 | 386 |
| 401 | 423 |
| 460 | 479 |
| 657 | 679 |
| 686 | 703 |
| 708 | 727 |
| 739 | 758 |
| 762 | 779 |
| 816 | 838 |
| 907 | 924 |
| 931 | 948 |
| 953 | 975 |
| 982 | 1004 |