You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001149_00840
You are here: Home > Sequence: MGYG000001149_00840
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Fusobacterium_B sp900554355 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae; Fusobacterium_B; Fusobacterium_B sp900554355 | |||||||||||
| CAZyme ID | MGYG000001149_00840 | |||||||||||
| CAZy Family | PL8 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 75537; End: 77498 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| PL8 | 365 | 594 | 6.2e-39 | 0.9111969111969112 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd01083 | GAG_Lyase | 1.78e-64 | 46 | 644 | 54 | 685 | Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase. |
| pfam02278 | Lyase_8 | 5.82e-37 | 365 | 590 | 5 | 248 | Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. |
| pfam08124 | Lyase_8_N | 1.80e-23 | 65 | 320 | 68 | 323 | Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVQ18397.1 | 1.02e-141 | 1 | 652 | 5 | 662 |
| QNM15126.1 | 7.54e-137 | 1 | 651 | 1 | 657 |
| ACZ00610.1 | 2.31e-74 | 7 | 630 | 4 | 614 |
| AVL42978.1 | 2.31e-74 | 7 | 630 | 4 | 614 |
| AEE16979.1 | 4.81e-71 | 6 | 589 | 8 | 617 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1F1S_A | 6.13e-37 | 51 | 516 | 142 | 626 | CrystalStructure Of Streptococcus Agalactiae Hyaluronate Lyase At 2.1 Angstrom Resolution. [Streptococcus agalactiae],1I8Q_A Crystal Structure Of Streptococcus Agalactiae Hyaluronate Lyase Complexed With Enzyme Product, Unsaturated Disaccharide Hyaluronan [Streptococcus agalactiae],1LXM_A Crystal Structure of Streptococcus agalactiae Hyaluronate Lyase Complexed with Hexasaccharide Unit of Hyaluronan [Streptococcus agalactiae] |
| 2E22_A | 2.23e-34 | 53 | 516 | 66 | 516 | Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1] |
| 2E24_A | 2.23e-34 | 53 | 516 | 66 | 516 | ChainA, Xanthan lyase [Bacillus sp. GL1] |
| 1X1H_A | 5.31e-34 | 53 | 516 | 66 | 516 | ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1] |
| 1J0M_A | 9.47e-34 | 53 | 516 | 66 | 516 | CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q53591 | 2.56e-36 | 51 | 516 | 312 | 796 | Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2 |
| Q9AQS0 | 1.78e-33 | 53 | 516 | 91 | 541 | Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1 |
| Q59801 | 3.40e-33 | 43 | 643 | 102 | 759 | Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1 |
| Q54873 | 2.62e-31 | 10 | 560 | 317 | 872 | Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000043 | 0.000003 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |