You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001151_00537
You are here: Home > Sequence: MGYG000001151_00537
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Ruminococcus_C sp000433635 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus_C; Ruminococcus_C sp000433635 | |||||||||||
| CAZyme ID | MGYG000001151_00537 | |||||||||||
| CAZy Family | CBM4 | |||||||||||
| CAZyme Description | Cellulose 1,4-beta-cellobiosidase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 63; End: 3149 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH9 | 356 | 895 | 6.6e-107 | 0.992822966507177 |
| CBM4 | 46 | 217 | 1.9e-22 | 0.9523809523809523 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00759 | Glyco_hydro_9 | 3.29e-71 | 361 | 895 | 4 | 374 | Glycosyl hydrolase family 9. |
| cd02850 | E_set_Cellulase_N | 1.22e-22 | 264 | 351 | 4 | 86 | N-terminal Early set domain associated with the catalytic domain of cellulase. E or "early" set domains are associated with the catalytic domain of cellulases at the N-terminal end. Cellulases are O-glycosyl hydrolases (GHs) that hydrolyze beta 1-4 glucosidic bonds in cellulose. They are usually categorized into either exoglucanases, which sequentially release terminal sugar units from the cellulose chain, or endoglucanases, which also attack the chain internally. The N-terminal domain of cellulase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others. |
| pfam02927 | CelD_N | 1.16e-21 | 262 | 346 | 3 | 83 | Cellulase N-terminal ig-like domain. |
| cd14256 | Dockerin_I | 5.75e-08 | 954 | 993 | 1 | 40 | Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex. |
| pfam02018 | CBM_4_9 | 6.42e-07 | 46 | 217 | 7 | 131 | Carbohydrate binding domain. This family includes diverse carbohydrate binding domains. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CBL17684.1 | 3.74e-271 | 1 | 976 | 1 | 915 |
| BAH56283.1 | 7.63e-232 | 37 | 899 | 170 | 1007 |
| ADU21576.1 | 9.45e-221 | 41 | 897 | 32 | 798 |
| AAR01216.1 | 6.24e-214 | 41 | 902 | 30 | 902 |
| CAS03458.1 | 2.67e-210 | 41 | 902 | 34 | 906 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UT9_A | 3.04e-140 | 262 | 899 | 7 | 605 | ChainA, CELLULOSE 1,4-BETA-CELLOBIOSIDASE [Acetivibrio thermocellus] |
| 1RQ5_A | 8.68e-140 | 262 | 901 | 7 | 607 | ChainA, Cellobiohydrolase [Acetivibrio thermocellus] |
| 6DHT_A | 1.71e-59 | 262 | 899 | 18 | 565 | Bacteroidesovatus GH9 Bacova_02649 [Bacteroides ovatus ATCC 8483] |
| 3X17_A | 1.53e-52 | 258 | 896 | 14 | 554 | Crystalstructure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium],3X17_B Crystal structure of metagenome-derived glycoside hydrolase family 9 endoglucanase [uncultured bacterium] |
| 5U0H_A | 1.25e-45 | 291 | 906 | 20 | 548 | Crystalstructure of GH family 9 endoglucanase J30 [Thermobacillus composti KWC4] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A3DCH1 | 8.33e-166 | 47 | 900 | 47 | 813 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celK PE=3 SV=1 |
| P0C2S1 | 2.50e-164 | 47 | 900 | 47 | 813 | Cellulose 1,4-beta-cellobiosidase OS=Acetivibrio thermocellus OX=1515 GN=celK PE=1 SV=1 |
| Q05156 | 3.81e-114 | 179 | 901 | 116 | 745 | Cellulase 1 OS=Streptomyces reticuli OX=1926 GN=cel1 PE=1 SV=1 |
| P14090 | 4.64e-112 | 55 | 901 | 196 | 910 | Endoglucanase C OS=Cellulomonas fimi (strain ATCC 484 / DSM 20113 / JCM 1341 / NBRC 15513 / NCIMB 8980 / NCTC 7547) OX=590998 GN=cenC PE=1 SV=2 |
| P10476 | 3.89e-105 | 264 | 902 | 39 | 602 | Endoglucanase A OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=celA PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000407 | 0.998674 | 0.000179 | 0.000319 | 0.000208 | 0.000174 |
