CAZyme Information: MGYG000001164_01491

Basic Information

• Species: Prevotella lascolaii
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella lascolaii
• CAZyme ID: MGYG000001164_01491
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1295	MGYG000001164_95|CGC1	144168.24	4.6684

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001164	3302780	MAG	Austria	Europe

• Gene Location: Start: 11270; End: 15157 Strand: -

Full Sequence      

MRKIYLFTVGIMMMILASSGVSAQESISLTETEQPGSFPIVTDNSTAVIVFDKSDAQVVE
TAATALAGDIKAVTGKEIGVGTTLTAGSSPIIAGTVGSSSLIDKLAAEGKIDVSGVKGKW
EAYGLQTVDNPTEGVERALVLFGSTPRGTAYAIFEVSRLMGVSPYIWWADVVPPHKDRLY
ASAGLSVTDEPSVKYRGIFINDEDWGFQPWAAKNMDPDRNNVGPNSYAKVMELLLRLRAN
TLWPAMHLCSEAFWANKANLPVAKKYDIVLGSSHCEQMLRNNEWEWRRWGDGTGTYENWN
YVTNKEKIQQYWEERVIESKGFDAIYTTGMRGVHDWAISGYPTTEDKVRGLTEIIGFQRE
LLQRHIGDPTTVPQIFIPYKEVLEAYNAGLQVPEDITLTWVDDNHGYIRQMPTKSEQARS
GGNGIYYHLSYWGTPQDYLWLCSTSPSLISYELSKGYEYGIRNLWIINVGDIKPAEAELE
FCMELAWDVDRWNPEEAHKFSRYWAAKTFGEEYADDLSDIKQEYYRLGAGGKPEHIFAVN
YTDEEKDRRIADYKAIVDKVDNLKARIPSELQDAYFEMIEYPVKGAYYMNVKTFRAAQSL
VLAKAGQRDKALEYAAEARKAYRQIELITDKYNNGIAGGKWNEMMDSKPRQQSQFYMPET
ATLSGISSVQKEIEKEETFSVAADKYTSVKGNVVTMEGLGMSGSSVTVWPIDETQYSADK
ASSAPYAEYDVEVKSGMNTISARCLPTFPIHPGYDLRVAVSVDGGEPEVCSLKTTATEGK
WNTTVLQGFNDATVTYNSDEDKTVSVRVYMLDPGVVLSQIYNRLPESADNSLTARLIKNN
DFELRTDGTPNPQGNTDRGIPYGWDHTGELTLGQNGLPSYGINQDAANPHGSNICWINSF
PMPEFFELSQTIPASEIEPGTYRVSCMMWMEENKKTSGRLFANNNVQYYGYESDYTRLLT
PGEINTYAGYAGQNGGGPFNLMPMEVYVTVAEGEDLKIGIRSGNRRNDGTTATDNAGWFK
VDNFRIEKVSGVPQPESEDLTLTKQLITNYDFELYNDNGTIKENTSGDTRRGTVYGIHGW
NISGRFPGDSYGINKDASNPHATNVCWFQAKNGTMPDGFELYQTIPADKLTPGRYMICCR
LWAEEGYLSTVRLFANDNVQYYGMDIDYGKNLTPGENNTFAGYIGGAPNSFVLQDMLVYV
DIAEGDDLKFGIRSGNTNADGSHSSEAKNGWFKTDFFRIHKVDATDGIETVAADGAGKKK
GVYNIKGQKIGDSLRDTPDLPAGIYVVDGRKTVVR

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	37	820	5.9e-231	0.9956958393113343

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	6.81e-167	189	535	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.67e-21	680	820	10	156	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	0.006	39	155	23	119	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNR82970.1	8.63e-257	12	820	14	830
QIL38270.1	1.66e-256	27	820	29	829
ARS42990.1	2.68e-252	2	820	4	830
ADY54265.1	1.51e-250	25	820	24	827
QNN40531.1	3.57e-250	11	820	12	832

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	6.19e-164	54	820	35	771	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4ZMH_A	1.55e-108	36	819	12	915	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
4C90_A	5.60e-101	1	820	12	832	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	5.97e-94	31	820	10	817	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	7.25e-93	31	820	9	816	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000280	0.999079	0.000181	0.000160	0.000139	0.000130

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001164_01491.