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CAZyme Information: MGYG000001170_00390
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS1603 sp900759005 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; UMGS1603; UMGS1603 sp900759005 | |||||||||||
| CAZyme ID | MGYG000001170_00390 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 7689; End: 11927 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 979 | 1204 | 9.2e-55 | 0.9282511210762332 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 1.35e-22 | 1222 | 1408 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 2.56e-21 | 979 | 1205 | 44 | 269 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 1.93e-16 | 978 | 1203 | 16 | 240 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG5542 | COG5542 | 3.89e-13 | 322 | 431 | 110 | 220 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG1807 | ArnT | 3.77e-08 | 997 | 1154 | 55 | 201 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUA53848.1 | 1.37e-226 | 4 | 1403 | 14 | 1363 |
| QTE75201.1 | 8.16e-213 | 2 | 1411 | 5 | 1423 |
| QTE71236.1 | 1.54e-212 | 16 | 1411 | 7 | 1408 |
| QUC68008.1 | 3.30e-211 | 9 | 1411 | 15 | 1423 |
| CQR52353.1 | 2.64e-207 | 7 | 1407 | 15 | 1270 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6P25_A | 7.58e-06 | 981 | 1216 | 72 | 310 | Structureof S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_A Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 1.21e-25 | 985 | 1398 | 73 | 509 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 1.21e-25 | 985 | 1398 | 73 | 509 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| Q8NRZ6 | 2.82e-24 | 1008 | 1407 | 99 | 516 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
| L8F4Z2 | 2.03e-23 | 985 | 1403 | 67 | 510 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000338 | 0.998987 | 0.000200 | 0.000163 | 0.000144 | 0.000136 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 212 | 229 |
| 239 | 261 |
| 289 | 311 |
| 326 | 348 |
| 360 | 382 |
| 406 | 428 |
| 441 | 463 |
| 467 | 486 |
| 493 | 512 |
| 517 | 539 |
| 552 | 574 |
| 626 | 648 |
| 655 | 674 |
| 698 | 720 |
| 733 | 755 |
| 796 | 815 |
| 1027 | 1049 |
| 1078 | 1097 |
| 1110 | 1129 |
| 1133 | 1150 |
| 1176 | 1198 |
| 1283 | 1302 |
| 1309 | 1327 |
| 1332 | 1351 |
| 1368 | 1390 |