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CAZyme Information: MGYG000001172_00626

You are here: Home > Sequence: MGYG000001172_00626

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Fusobacterium sp000235465
Lineage Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae; Fusobacterium; Fusobacterium sp000235465
CAZyme ID MGYG000001172_00626
CAZy Family GT9
CAZyme Description Lipopolysaccharide core heptosyltransferase RfaQ
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
343 39516.11 9.3768
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001172 2065216 MAG Austria Europe
Gene Location Start: 4497;  End: 5528  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001172_00626.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 71 312 9.6e-49 0.9688888888888889

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG0859 RfaF 5.14e-74 1 332 2 331
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
cd03789 GT9_LPS_heptosyltransferase 2.08e-71 2 329 1 277
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
pfam01075 Glyco_transf_9 5.91e-25 71 299 3 236
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.
TIGR02195 heptsyl_trn_II 3.40e-24 2 323 1 325
lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK10422 PRK10422 1.10e-22 3 289 8 306
lipopolysaccharide core biosynthesis protein; Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ATV70235.1 3.72e-238 1 342 1 342
AVQ24559.1 8.08e-238 1 342 1 342
ATV35668.1 1.51e-237 1 342 1 342
ATV61439.1 1.51e-237 1 342 1 342
ATV67616.1 1.76e-236 1 342 1 342

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3TOV_A 1.58e-15 2 295 10 311
Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9R9D5 1.94e-11 10 289 3 294
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1
P45042 1.18e-10 1 332 1 345
ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1
P37421 2.87e-10 1 332 1 344
ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1
P25742 9.40e-09 12 298 5 303
Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2
P37692 4.08e-08 1 327 1 339
ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000013 0.000038 0.000001 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001172_00626.