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CAZyme Information: MGYG000001186_02373

You are here: Home > Sequence: MGYG000001186_02373

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Agathobacter sp900547695
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Agathobacter; Agathobacter sp900547695
CAZyme ID MGYG000001186_02373
CAZy Family GT51
CAZyme Description Monofunctional biosynthetic peptidoglycan transglycosylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
834 MGYG000001186_16|CGC1 91122.92 4.3475
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001186 3291648 MAG Austria Europe
Gene Location Start: 12078;  End: 14582  Strand: -

Full Sequence      Download help

MAKKKKKKKQ  HRFFWFMIKF  QIFLMIIVLG  GLGYYFFGGY  AGQVQKLRSE  AVELVKQSDK60
NTFVPARTSL  LYDTNGTLIS  ETASEKDAEY  VKYEDIPANF  VTAMVSIEDK  KFYSHNGVDY120
KAIIRAAKAI  IQDGKVSQGG  STITMQLARN  IYLDTGKTWQ  RKVKEIFIAM  QLEKKYSKND180
IMEFYLNNIY  FANGYYGIEA  ACHGYFNCEL  KDLDLSQTAF  LCSIPNSPTY  YDPIVNQDHT240
IKRRNLILKN  MREDGKITQA  EYEKAVSEEI  VLNVSKSDDT  VKNNYVDTYA  YFCATEALME300
NEGFKFKYYF  DSTDDEKKYD  ESYDELYSYC  QKKLYSEGYK  IYTSIDLDKQ  EKLQDSVDTA360
LADFTDVTDD  GMYKLQGAAV  SIDNSNGYVV  AIVGGRSQDF  TNHTLNRAFQ  SHRQPGSSIK420
PLIVYTPAFE  NGYTPDSVVD  DHKFDGGPSN  AGDTYHGDVT  IRYAVEQSLN  TVAWQVYEDV480
TPEKGLKYLK  NMNFTNIVDS  DYTIATALGG  FTTGTSPLEM  ASAYATLEND  GLYRKPTCVT540
SIVDGNENIV  YTSSPVETVI  YKETASRMMT  DVLTGVMSDG  TGRKAKLEND  MPCAGKTGTT600
NDKKDGWFCG  YTRYYTTSVW  VGCDMPESVS  SLTGSSYPAQ  IWKQYMDDIH  DGLTPLDFLP660
YAQMSQDYSD  NDDSTYEENA  QELQDEQTPD  DGAAAQTPDA  ATGNGATTDQ  SQQTTPDQST720
TGTTTPSGNT  NTTDTTGGNT  GAAGGNTGSA  TDNTTPGDTT  NSGTGNTTGG  NAADATGADT780
TNTNGGSTGD  TTGGNTDSTT  GGGAGNTGDN  TGGNTGADTG  NTGDGSSPAD  QTTP834

Enzyme Prediction      help

No EC number prediction in MGYG000001186_02373.

CAZyme Signature Domains help

Created with Snap418312516620825029133337541745850054258362566770875079276252GT51
Family Start End Evalue family coverage
GT51 76 252 8.6e-66 0.9887005649717514

CDD Domains      download full data without filtering help

Created with Snap418312516620825029133337541745850054258362566770875079287650PBP_1a_fam12702MrcB65660MrcA69666PbpC75252Transgly
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02074 PBP_1a_fam 0.0 87 650 1 529
penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG0744 MrcB 7.67e-170 12 702 10 654
Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis].
COG5009 MrcA 4.35e-139 65 660 45 729
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis].
COG4953 PbpC 9.55e-80 69 666 37 577
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis].
pfam00912 Transgly 8.85e-73 75 252 1 177
Transglycosylase. The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.

CAZyme Hits      help

Created with Snap418312516620825029133337541745850054258362566770875079216702CBK89800.1|GT5116674ACR76878.1|GT5116674CBK93334.1|GT5116679CBL14325.1|GT5137680CBL07484.1|GT51
Hit ID E-Value Query Start Query End Hit Start Hit End
CBK89800.1 0.0 16 702 18 698
ACR76878.1 0.0 16 674 18 676
CBK93334.1 0.0 16 674 18 676
CBL14325.1 2.01e-276 16 679 4 664
CBL07484.1 4.85e-271 37 680 37 685

PDB Hits      download full data without filtering help

Created with Snap4183125166208250291333375417458500542583625667708750792716464OON_A1716363ZG8_B716523UDF_A676587U4H_A1716363ZG7_B
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4OON_A 1.24e-73 71 646 23 719
Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1]
3ZG8_B 1.49e-71 171 636 2 445
CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes]
3UDF_A 4.11e-69 71 652 23 718
ChainA, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDF_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDI_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UDX_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE0_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_A Chain A, Penicillin-binding protein 1a [Acinetobacter baumannii],3UE1_B Chain B, Penicillin-binding protein 1a [Acinetobacter baumannii]
7U4H_A 6.89e-69 67 658 19 769
ChainA, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX],7U4H_B Chain B, Penicillin-binding protein 1A (Pbp1a) [Chlamydia trachomatis D/UW-3/CX]
3ZG7_B 8.83e-66 171 636 2 445
CrystalStructure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the apo form [Listeria monocytogenes]

Swiss-Prot Hits      download full data without filtering help

Created with Snap418312516620825029133337541745850054258362566770875079243643sp|P40750|PBPD_BACSU59669sp|P38050|PBPF_BACSU62646sp|O66874|PBPA_AQUAE59652sp|P39793|PBPA_BACSU69664sp|A7FY32|PBPA_CLOB1
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P40750 1.50e-114 43 643 30 617
Penicillin-binding protein 4 OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpD PE=1 SV=2
P38050 7.74e-87 59 669 39 630
Penicillin-binding protein 1F OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpF PE=2 SV=2
O66874 1.34e-81 62 646 38 664
Penicillin-binding protein 1A OS=Aquifex aeolicus (strain VF5) OX=224324 GN=mrcA PE=1 SV=1
P39793 3.64e-79 59 652 67 646
Penicillin-binding protein 1A/1B OS=Bacillus subtilis (strain 168) OX=224308 GN=ponA PE=1 SV=1
A7FY32 1.18e-77 69 664 57 652
Penicillin-binding protein 1A OS=Clostridium botulinum (strain ATCC 19397 / Type A) OX=441770 GN=pbpA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.921130 0.000433 0.000478 0.000005 0.000002 0.077989

TMHMM  Annotations      download full data without filtering help

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