CAZyme Information: MGYG000001193_00584

Basic Information

• Species: UBA4285 sp900545225
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; UBA4285; UBA4285 sp900545225
• CAZyme ID: MGYG000001193_00584
• CAZy Family: GT0
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
431	MGYG000001193_2|CGC2	49166.28	9.4173

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001193	1467080	MAG	Austria	Europe

• Gene Location: Start: 162884; End: 164179 Strand: +

Full Sequence      

MDLSSTILEVGHKVRPVVGKIVPQFIIDKIYAKVTSNTGRMAVHKFKTEPKKKFKPNKFK
RGINLVGDIESATGLGQSIRLLAGVMEDQNIPFATHQFTLNENGFSQENPFADKNTKGYP
YGINVFHINTADFPSAYLKLGPKPWSEHYNIAHWVWELEELPEHWIPYMCMANEFWTPSE
FASSVFRKYTKKKVVTVPHSVTAPYDEKYDRKYFGLPEDKFLFLTMYASDSLVERKNPQA
VVRAFKKAFKKNDPSVGLVIKVVPSKHRTGDIDELKRMTAGYNNVYFLTGEYEKIEVNSM
LRDVDAYVSLHRSEGFGLTLAESMMLGTPTISTNWSGNVEFQNEDTACMVDYKLVDVGKN
IPLFPEGSKWAEASADHAAEYMKKLYSDKEFYNRIKENGLKSINEQLSKESVGKIVNKRI
NAIYNKALKNQ

Enzyme Prediction     

No EC number prediction in MGYG000001193_00584.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd03801	GT4_PimA-like	6.48e-25	123	412	86	357	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
COG0438	RfaB	8.83e-23	118	431	97	381	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd01635	Glycosyltransferase_GTB-type	4.73e-18	175	350	62	234	glycosyltransferase family 1 and related proteins with GTB topology. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
pfam00534	Glycos_transf_1	5.36e-17	232	401	11	157	Glycosyl transferases group 1. Mutations in this domain of PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.
cd03817	GT4_UGDG-like	3.47e-14	171	402	147	355	UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ACR71127.1	1.07e-123	1	424	1	427
ANY70499.1	2.76e-93	61	425	62	426
QQZ62154.1	2.76e-93	62	423	61	422
AZS17521.1	1.58e-89	62	423	64	425
BBI36185.1	1.25e-88	62	423	63	424

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000055	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001193_00584.