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CAZyme Information: MGYG000001205_00845
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Gemmiger; | |||||||||||
| CAZyme ID | MGYG000001205_00845 | |||||||||||
| CAZy Family | GT11 | |||||||||||
| CAZyme Description | O-antigen biosynthesis glycosyltransferase WbnK | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 16310; End: 17233 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT11 | 1 | 304 | 4.5e-55 | 0.9963768115942029 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11301 | Fut1_Fut2_like | 3.46e-37 | 6 | 292 | 7 | 260 | Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
| pfam01531 | Glyco_transf_11 | 8.03e-25 | 1 | 305 | 1 | 298 | Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTF99525.1 | 2.56e-35 | 1 | 304 | 1 | 287 |
| CDN51206.1 | 1.01e-34 | 1 | 304 | 1 | 288 |
| AEV24483.1 | 4.65e-34 | 2 | 303 | 26 | 310 |
| AKV07576.1 | 5.44e-34 | 1 | 301 | 1 | 285 |
| QOT78612.1 | 8.35e-34 | 1 | 304 | 1 | 292 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q58YV9 | 3.57e-11 | 178 | 301 | 172 | 299 | O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1 |
| Q866E1 | 2.55e-06 | 91 | 274 | 143 | 319 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Alouatta belzebul OX=30590 GN=FUT1 PE=3 SV=1 |
| Q866E4 | 2.55e-06 | 91 | 274 | 143 | 319 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Alouatta caraya OX=9502 GN=FUT1 PE=3 SV=1 |
| O77487 | 3.21e-06 | 176 | 306 | 196 | 335 | Galactoside alpha-(1,2)-fucosyltransferase 2 OS=Pongo pygmaeus OX=9600 GN=FUT2 PE=3 SV=1 |
| O77485 | 4.29e-06 | 176 | 306 | 196 | 335 | Galactoside alpha-(1,2)-fucosyltransferase 2 OS=Pan troglodytes OX=9598 GN=FUT2 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000061 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |