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CAZyme Information: MGYG000001218_00456
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | RUG11247 sp902767315 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; RUG11247; RUG11247 sp902767315 | |||||||||||
| CAZyme ID | MGYG000001218_00456 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 15195; End: 19040 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 864 | 1085 | 1.7e-55 | 0.9192825112107623 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam16192 | PMT_4TMC | 7.38e-24 | 1096 | 1274 | 1 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1928 | PMT1 | 1.21e-19 | 863 | 1086 | 60 | 267 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 4.78e-17 | 863 | 1084 | 16 | 238 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| COG5542 | COG5542 | 2.03e-13 | 274 | 585 | 71 | 372 | Mannosyltransferase related to Gpi18 [Carbohydrate transport and metabolism]. |
| COG4346 | COG4346 | 5.90e-10 | 886 | 1222 | 129 | 404 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QSF45552.1 | 3.03e-239 | 2 | 1273 | 6 | 1268 |
| ASA25569.1 | 7.32e-239 | 1 | 1273 | 5 | 1263 |
| CQR52353.1 | 6.92e-238 | 26 | 1273 | 30 | 1270 |
| QUL55595.1 | 4.92e-235 | 26 | 1273 | 30 | 1273 |
| AIQ39188.1 | 4.26e-233 | 10 | 1273 | 12 | 1274 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 3.30e-27 | 870 | 1265 | 73 | 510 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 3.30e-27 | 870 | 1265 | 73 | 510 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 1.33e-23 | 870 | 1264 | 67 | 503 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
| Q8NRZ6 | 1.53e-17 | 893 | 1273 | 99 | 516 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000198 | 0.999268 | 0.000137 | 0.000144 | 0.000129 | 0.000125 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 5 | 22 |
| 212 | 229 |
| 246 | 268 |
| 326 | 348 |
| 355 | 377 |
| 382 | 404 |
| 444 | 463 |
| 510 | 532 |
| 539 | 561 |
| 581 | 600 |
| 621 | 643 |
| 679 | 698 |
| 912 | 934 |
| 958 | 980 |
| 993 | 1012 |
| 1016 | 1035 |
| 1059 | 1081 |
| 1149 | 1171 |
| 1184 | 1201 |
| 1205 | 1227 |
| 1234 | 1256 |