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CAZyme Information: MGYG000001222_00477

You are here: Home > Sequence: MGYG000001222_00477

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UMGS1326 sp900550775
Lineage Bacteria; Firmicutes_A; Clostridia; Monoglobales; Monoglobaceae; UMGS1326; UMGS1326 sp900550775
CAZyme ID MGYG000001222_00477
CAZy Family PL8
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1313 MGYG000001222_9|CGC1 143662.66 4.6389
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001222 2203618 MAG Austria Europe
Gene Location Start: 6592;  End: 10533  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001222_00477.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 749 932 4.6e-50 0.6138996138996139
CBM32 952 1068 5.8e-18 0.9112903225806451

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 2.03e-105 383 1241 1 693
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam02278 Lyase_8 8.46e-45 748 928 2 158
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam08124 Lyase_8_N 2.80e-33 391 709 1 323
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam02884 Lyase_8_C 2.00e-17 1187 1244 1 62
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam00754 F5_F8_type_C 1.54e-13 951 1067 5 127
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QNK57789.1 1.92e-72 384 1242 36 730
BAJ75813.1 4.46e-72 380 1276 49 776
QNK56376.1 4.04e-71 377 1242 34 751
AZS18086.1 1.15e-70 364 1242 10 733
BBH21831.1 1.25e-69 352 1284 1 781

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6F2P_A 2.90e-70 382 1245 4 700
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
1X1H_A 1.69e-57 382 1313 2 750
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]
1J0M_A 2.27e-57 382 1313 2 750
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
2E22_A 5.49e-57 382 1313 2 750
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
2E24_A 5.49e-57 382 1313 2 750
ChainA, Xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 2.08e-55 382 1313 27 775
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q54873 2.05e-37 369 926 276 818
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
Q53591 6.89e-37 357 948 225 819
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
Q59801 6.13e-32 383 930 48 604
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
P0CZ01 1.06e-10 1094 1247 577 751
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.835752 0.132139 0.028107 0.000570 0.000347 0.003104

TMHMM  Annotations      download full data without filtering help

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