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CAZyme Information: MGYG000001240_01063

You are here: Home > Sequence: MGYG000001240_01063

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella sp900557405
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900557405
CAZyme ID MGYG000001240_01063
CAZy Family GH137
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1365 MGYG000001240_26|CGC1 156012.23 8.7651
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001240 2497614 MAG Austria Europe
Gene Location Start: 21729;  End: 25826  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.31 3.2.1.185

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH137 36 382 9.2e-147 0.9882352941176471
GH2 390 835 6.9e-74 0.511968085106383
CBM57 1056 1214 1e-35 0.9863945578231292

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 1.14e-36 383 808 2 431
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 7.05e-25 436 806 112 472
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam11721 Malectin 4.99e-24 1054 1217 1 156
Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognizes and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan.
PRK10150 PRK10150 3.70e-20 437 874 69 536
beta-D-glucuronidase; Provisional
pfam02836 Glyco_hydro_2_C 7.40e-17 664 941 5 297
Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUR43084.1 0.0 37 1365 23 1399
QRN01915.1 0.0 37 1365 23 1399
QNL37683.1 0.0 37 1365 23 1399
SCV09658.1 0.0 37 1365 23 1399
QIU95869.1 0.0 37 1365 23 1404

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5MUI_A 4.51e-179 37 386 29 378
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482]
5MT2_A 1.97e-172 37 386 29 378
Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482],5MUJ_A BT0996 RGII Chain B Complex [Bacteroides thetaiotaomicron VPI-5482]
3CMG_A 1.92e-40 391 952 4 579
Crystalstructure of putative beta-galactosidase from Bacteroides fragilis [Bacteroides fragilis NCTC 9343]
5Z1A_A 2.19e-40 391 952 23 598
Thecrystal structure of Bacteroides fragilis beta-glucuronidase in complex with uronic isofagomine [Bacteroides fragilis NCTC 9343]
6D50_A 1.77e-37 382 1201 24 868
Bacteroidesuniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii],6D50_B Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A7LXS9 1.32e-28 437 778 106 437
Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09 1.78e-28 360 799 19 451
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
P26257 3.64e-25 449 992 71 590
Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1
Q56307 2.36e-21 394 787 74 450
Beta-galactosidase OS=Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) OX=243274 GN=lacZ PE=1 SV=2
P06864 2.99e-21 399 779 87 450
Evolved beta-galactosidase subunit alpha OS=Escherichia coli (strain K12) OX=83333 GN=ebgA PE=1 SV=4

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000224 0.999197 0.000152 0.000153 0.000136 0.000128

TMHMM  Annotations      download full data without filtering help

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