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CAZyme Information: MGYG000001262_02065

You are here: Home > Sequence: MGYG000001262_02065

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Sphingomonas ginsenosidimutans
Lineage Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; Sphingomonadaceae; Sphingomonas; Sphingomonas ginsenosidimutans
CAZyme ID MGYG000001262_02065
CAZy Family AA2
CAZyme Description Catalase-peroxidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
744 MGYG000001262_82|CGC1 81157 4.7949
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001262 3667136 MAG Italy Europe
Gene Location Start: 8696;  End: 10930  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001262_02065.

CAZyme Signature Domains help

Family Start End Evalue family coverage
AA2 85 189 2.3e-17 0.403921568627451

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG0376 KatG 0.0 1 742 6 730
Catalase (peroxidase I) [Inorganic ion transport and metabolism].
cd08200 catalase_peroxidase_2 0.0 441 738 1 297
C-terminal non-catalytic domain of catalase-peroxidases. This is a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Catalase-peroxidases can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. These enzymes are found in many archaeal and bacterial organisms where they neutralize potentially lethal hydrogen peroxide molecules generated during photosynthesis or stationary phase. Along with related intracellular fungal and plant peroxidases, catalase-peroxidases belong to plant peroxidase superfamily. Unlike the eukaryotic enzymes, they are typically comprised of two homologous domains that probably arose via a single gene duplication event. The heme binding motif is present only in the N-terminal domain; the function of the C-terminal domain is not clear.
cd00649 catalase_peroxidase_1 0.0 25 437 3 409
N-terminal catalytic domain of catalase-peroxidases. This is a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Catalase-peroxidases can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. These enzymes are found in many archaeal and bacterial organisms, where they neutralize potentially lethal hydrogen peroxide molecules generated during photosynthesis or stationary phase. Along with related intracellular fungal and plant peroxidases, catalase-peroxidases belong to class I of the plant peroxidase superfamily. Unlike the eukaryotic enzymes, they are typically comprised of two homologous domains that probably arose via a single gene duplication event. The heme binding motif is present only in the N-terminal domain; the function of the C-terminal domain is not clear.
PRK15061 PRK15061 0.0 11 742 5 726
catalase/peroxidase.
TIGR00198 cat_per_HPI 0.0 25 741 13 713
catalase/peroxidase HPI. As catalase, this enzyme catalyzes the dismutation of two molecules of hydrogen peroxide to dioxygen and two molecules of water. As a peroxidase, it uses hydrogen peroxide to oxidize donor compounds and produce water. KatG from E. coli is a homotetramer with two non-covalently associated iron protoheme IX groups per tetramer, but the ortholog from Synechococcus sp. is a homodimer with one protoheme. Important sites (numbered according to E. coli KatG) include heme ligands His-106 and His-267 and active site Trp-318. Note that the translation PID:g296476 from accession X71420 from Rhodobacter capsulatus B10 contains extensive frameshift differences from the rest of the orthologous family. [Cellular processes, Detoxification]

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QZY04649.1 3.97e-294 26 741 3 714
QPC71243.1 2.03e-272 25 741 55 773
BCS24344.1 1.02e-31 65 416 6 264
BCS01357.1 1.67e-30 65 416 6 264
BCS13101.1 1.67e-30 65 416 6 264

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5SXX_A 0.0 25 742 16 728
Crystalstructure of the E198A variant of Burkholderia pseudomallei catalase-peroxidase KatG with INH [Burkholderia pseudomallei 1710b],5SXX_B Crystal structure of the E198A variant of Burkholderia pseudomallei catalase-peroxidase KatG with INH [Burkholderia pseudomallei 1710b]
5SYW_A 0.0 25 742 16 728
Crystalstructure of Burkhoderia pseudomallei KatG variant Q233E [Burkholderia pseudomallei 1710b],5SYW_B Crystal structure of Burkhoderia pseudomallei KatG variant Q233E [Burkholderia pseudomallei 1710b]
5SYV_A 0.0 25 742 16 728
Crystalstructure of Burkholderia pseudomallei KatG N240D variant [Burkholderia pseudomallei 1710b],5SYV_B Crystal structure of Burkholderia pseudomallei KatG N240D variant [Burkholderia pseudomallei 1710b]
5SYU_A 0.0 25 742 16 728
Crystalstructure of Burkholderia pseudomallei KatG E242Q variant [Burkholderia pseudomallei 1710b],5SYU_B Crystal structure of Burkholderia pseudomallei KatG E242Q variant [Burkholderia pseudomallei 1710b]
5SYY_A 0.0 25 742 16 728
Crystalstructure of the S324G variant of catalase-peroxidase from B. pseudomallei [Burkholderia pseudomallei 1710b],5SYY_B Crystal structure of the S324G variant of catalase-peroxidase from B. pseudomallei [Burkholderia pseudomallei 1710b]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P14412 0.0 12 744 12 728
Catalase-peroxidase OS=Geobacillus stearothermophilus OX=1422 GN=katG PE=1 SV=2
Q1GR67 0.0 6 742 3 731
Catalase-peroxidase OS=Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256) OX=317655 GN=katG PE=3 SV=1
Q1GCU3 0.0 1 741 1 737
Catalase-peroxidase OS=Ruegeria sp. (strain TM1040) OX=292414 GN=katG PE=3 SV=1
Q1BQP0 0.0 25 741 16 725
Catalase-peroxidase 2 OS=Burkholderia cenocepacia (strain AU 1054) OX=331271 GN=katG2 PE=3 SV=1
Q24YU1 0.0 25 742 20 730
Catalase-peroxidase OS=Desulfitobacterium hafniense (strain Y51) OX=138119 GN=katG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000064 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001262_02065.