Species | DNF00809 sp001552935 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Actinobacteriota; Coriobacteriia; Coriobacteriales; Eggerthellaceae; DNF00809; DNF00809 sp001552935 | |||||||||||
CAZyme ID | MGYG000001278_00528 | |||||||||||
CAZy Family | GT28 | |||||||||||
CAZyme Description | Processive diacylglycerol beta-glucosyltransferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 561; End: 1889 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT28 | 260 | 394 | 3e-26 | 0.8471337579617835 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd17507 | GT28_Beta-DGS-like | 9.92e-51 | 35 | 415 | 1 | 364 | beta-diglucosyldiacylglycerol synthase and similar proteins. beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
COG0707 | MurG | 1.91e-32 | 37 | 413 | 4 | 354 | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]. |
PRK13609 | PRK13609 | 3.21e-27 | 33 | 415 | 5 | 370 | diacylglycerol glucosyltransferase; Provisional |
PRK13608 | PRK13608 | 4.19e-25 | 35 | 413 | 8 | 368 | diacylglycerol glucosyltransferase; Provisional |
cd03785 | GT28_MurG | 9.06e-24 | 187 | 409 | 136 | 350 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QKF07799.1 | 1.50e-199 | 33 | 442 | 35 | 444 |
QTU84801.1 | 1.15e-176 | 30 | 442 | 36 | 461 |
ACV55211.1 | 3.78e-176 | 1 | 442 | 61 | 516 |
QOS69492.1 | 1.19e-175 | 33 | 442 | 55 | 478 |
BAK44346.1 | 3.30e-172 | 11 | 442 | 10 | 465 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
3S2U_A | 2.23e-06 | 194 | 413 | 143 | 354 | Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
B9DQ98 | 1.07e-21 | 35 | 390 | 8 | 345 | Processive diacylglycerol beta-glucosyltransferase OS=Staphylococcus carnosus (strain TM300) OX=396513 GN=ugtP PE=3 SV=1 |
Q4L524 | 6.64e-21 | 35 | 390 | 8 | 345 | Processive diacylglycerol beta-glucosyltransferase OS=Staphylococcus haemolyticus (strain JCSC1435) OX=279808 GN=ugtP PE=3 SV=1 |
Q49WE6 | 1.84e-19 | 35 | 413 | 8 | 368 | Processive diacylglycerol beta-glucosyltransferase OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) OX=342451 GN=ugtP PE=3 SV=1 |
Q6GI67 | 2.48e-19 | 35 | 425 | 8 | 379 | Processive diacylglycerol beta-glucosyltransferase OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=ugtP PE=3 SV=1 |
Q5HQE7 | 4.52e-19 | 35 | 425 | 8 | 379 | Processive diacylglycerol beta-glucosyltransferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=ugtP PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000062 | 0.000002 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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