CAZyme Information: MGYG000001283_00333

Basic Information

• Species: Scardovia wiggsiae
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Scardovia; Scardovia wiggsiae
• CAZyme ID: MGYG000001283_00333
• CAZy Family: GT2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
359	MGYG000001283_2|CGC4	40296.06	8.9435

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001283	1508369	MAG	Italy	Europe

• Gene Location: Start: 85605; End: 86684 Strand: -

Full Sequence      

MESMTVQNSHQAHAVTDRLSMVIVTYKRQELLQELCDSIKGLTIKPWRVIIVDNEASADT
QRIAEALEKALSVPGGRHASQRQPSSGSAPSADAKGGTDRVVYIPMKENTGGAGGFYRGV
KEAYDRGSEWFWVMDDDVAALPDALEKLSPWMKNFEAIQGGRYDFDGGDFYWQYQTIVPL
GIPNPFSPPKFGASGFRPMNSMCFEGGLFKRSVVDKAGFPDPRFFIAWDDANFGYLASKV
TEPIIIRDKVLRRTRTLANIDIAGLPQINSMSDVKRFYLMRNRGFLARYYMAHGDYYPAA
FALGNAITFCKELIRLFTVDRKSLRSGFIQICKGWAAEHRILHDPRWKPMPVPPESAGN

Enzyme Prediction     

No EC number prediction in MGYG000001283_00333.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GT2	20	216	2e-21	0.9823529411764705

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd04185	GT_2_like_b	3.71e-58	22	286	2	202	Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.
COG1216	GT2	3.89e-25	16	325	2	279	Glycosyltransferase, GT2 family [Carbohydrate transport and metabolism].
pfam00535	Glycos_transf_2	2.68e-18	20	214	1	164	Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.
cd02526	GT2_RfbF_like	1.67e-12	22	287	2	237	RfbF is a putative dTDP-rhamnosyl transferase. Shigella flexneri RfbF protein is a putative dTDP-rhamnosyl transferase. dTDP rhamnosyl transferases of Shigella flexneri add rhamnose sugars to N-acetyl-glucosamine in the O-antigen tetrasaccharide repeat. Lipopolysaccharide O antigens are important virulence determinants for many bacteria. The variations of sugar composition, the sequence of the sugars and the linkages in the O antigen provide structural diversity of the O antigen.
cd00761	Glyco_tranf_GTA_type	3.83e-12	22	148	2	98	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
BAR06125.1	4.34e-191	16	351	41	356
BAR05971.1	7.41e-183	18	353	22	348
BBA47869.1	8.87e-150	5	351	12	346
BAQ98963.1	8.87e-150	5	351	12	346
VEG16979.1	9.85e-150	5	351	15	349

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A0R5Z2	8.42e-13	16	286	4	254	Galactofuranosyltransferase GlfT1 OS=Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) OX=246196 GN=glfT1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000052	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001283_00333.