logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001304_00023

You are here: Home > Sequence: MGYG000001304_00023

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Erysipelatoclostridium spiroforme
Lineage Bacteria; Firmicutes; Bacilli; Erysipelotrichales; Erysipelatoclostridiaceae; Erysipelatoclostridium; Erysipelatoclostridium spiroforme
CAZyme ID MGYG000001304_00023
CAZy Family GH84
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
1123 MGYG000001304_1|CGC1 122816.66 4.1566
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001304 2507485 Isolate not provided North America
Gene Location Start: 26830;  End: 30201  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001304_00023.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH84 187 484 6.5e-107 0.9932203389830508
CBM32 722 847 7.9e-23 0.9354838709677419

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam07555 NAGidase 1.11e-136 187 483 1 293
beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
pfam00754 F5_F8_type_C 1.70e-19 722 843 1 124
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
pfam02838 Glyco_hydro_20b 1.86e-15 38 163 1 107
Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold.
COG3291 COG3291 5.91e-14 593 783 52 243
PKD repeat [Function unknown].
smart00089 PKD 6.42e-09 627 705 1 79
Repeats in polycystic kidney disease 1 (PKD1) and other proteins. Polycystic kidney disease 1 protein contains 14 repeats, present elsewhere such as in microbial collagenases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QCJ44459.1 1.54e-307 41 966 41 956
AZU64318.1 1.95e-297 41 936 42 938
ASY51512.1 3.97e-180 7 623 2 620
BAB80940.1 3.97e-180 7 623 2 620
QQA11111.1 3.97e-180 7 623 2 620

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2CBI_A 3.13e-185 39 623 14 590
Structureof the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBI_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBJ_A Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2CBJ_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2V5C_A Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2V5C_B Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2VUR_A Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2VUR_B Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2X0Y_A Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens],2X0Y_B Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens]
2J62_A 4.41e-185 39 623 14 590
Structureof a bacterial O-glcnacase in complex with glcnacstatin [Clostridium perfringens],2J62_B Structure of a bacterial O-glcnacase in complex with glcnacstatin [Clostridium perfringens],2WB5_A GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation [Clostridium perfringens],2WB5_B GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation [Clostridium perfringens]
5OXD_A 1.52e-184 39 621 16 590
Complexof a C. perfringens O-GlcNAcase with a fragment hit [Clostridium perfringens]
2XPK_A 2.45e-184 39 623 14 590
Cell-penetrant,nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases [Clostridium perfringens],2XPK_B Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases [Clostridium perfringens]
6RHE_A 3.23e-184 39 622 16 591
CpOGAD298N in complex with hOGA-derived S-GlcNAc peptide [Clostridium perfringens ATCC 13124]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8XL08 7.94e-181 7 623 2 620
O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1
Q0TR53 1.69e-179 7 623 2 620
O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1
Q89ZI2 8.51e-85 38 543 23 503
O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1
P26831 3.27e-40 2 541 4 558
Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2
O60502 6.76e-33 188 452 63 331
Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000282 0.999073 0.000179 0.000172 0.000155 0.000137

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001304_00023.