logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001313_00818

You are here: Home > Sequence: MGYG000001313_00818

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides eggerthii
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides eggerthii
CAZyme ID MGYG000001313_00818
CAZy Family GH2
CAZyme Description Beta-galactosidase BoGH2A
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
787 MGYG000001313_17|CGC13 89849.62 6.2167
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001313 4157999 Isolate not provided not provided
Gene Location Start: 970826;  End: 973189  Strand: +

Full Sequence      Download help

MRRLLLLCYL  VTAGVVGIFA  QGENRLKDNF  DFDWKFSLND  DRQYADPVYN  DQSWEDIQLP60
HDWSIKLNFD  HSISGSAAHL  PGGIGWYRKA  FIVPASYKNK  SVSVLFDGIF  HQSDVYINGK120
HLGFRPYGFC  SIEYDLTPYL  KYGEKNIISV  RVDRSGKDNI  ARWYTGSGIY  RHAWLIVTNP180
MHVINNGTYV  TTPEIDAQRA  CVAVVTSLTN  TSHQEETATL  MQYILDKEGK  VVAKSDNRKV240
TVQPKDTVDV  TQQLNLENPV  LWSIDTPSMY  TMKTIVKIGR  KTVDDYRTPF  GVRTIEFTAD300
RGFFLNGQQV  KLKGLCLHQD  AGALGTAVPD  RSSERRLEIL  KEYGCNAIRC  AHNQPSPEFL360
DMCDRMGFIV  IDEAFDKWKS  GYYAKYFDKW  WQTDMEDMLL  RDRNHPSVVL  WSIGNELQEA420
WESSDEGVER  AKMLQDFVHQ  KEPSRMAILS  AQNNHQEKFS  GVTDVIGYNY  LEARMLSDHK480
KFPERRFMIT  EELPYYSGEE  GNIRSYTPYN  PWNIIAENEF  VAGGFIWSGV  DYLGEAASRE540
SHGWPNGLFD  ICMFEKPRAA  YHRAMWNNKP  LVSIAFLDPS  LDIDHGRDLW  QWPKMASHWN600
LPRTYFGQVI  QVCTITNCEE  VEMFMNGKSM  GKQKTADFTN  NTIIWNIPYR  PGTLEAKGYN660
DGKEVAAYQL  ATSKDTDSLI  LTPDRTMIKA  DGQDLSHIAI  QLYDEDGKPV  QTDDKELTVT720
VEGDGRFLGI  DNGDLRRKNS  FSGNRLKTYF  GKALVVVQSL  RKAGTMTVSV  EMEGKATPYV780
VTIQSVR787

Enzyme Prediction      help

EC 3.2.1.23

CAZyme Signature Domains help

Created with Snap397811815719623627531435439343247251155059062966870874723570GH2
Family Start End Evalue family coverage
GH2 23 570 3.8e-116 0.6156914893617021

CDD Domains      download full data without filtering help

Created with Snap397811815719623627531435439343247251155059062966870874733535LacZ34532ebgA34416PRK10150681774Glyco_hydro2_C534180Glyco_hydro_2_N
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 1.16e-70 33 535 33 505
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 1.58e-46 34 532 48 548
cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK10150 PRK10150 1.57e-43 34 416 19 417
beta-D-glucuronidase; Provisional
pfam18565 Glyco_hydro2_C5 4.01e-32 681 774 3 96
Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.
pfam02837 Glyco_hydro_2_N 5.87e-27 34 180 8 169
Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.

CAZyme Hits      help

Created with Snap39781181571962362753143543934324725115505906296687087471787QRQ48869.1|GH220785QJR79164.1|GH22783QRQ58661.1|GH22783SCV06580.1|GH22783QUT25652.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
QRQ48869.1 0.0 1 787 1 787
QJR79164.1 0.0 20 785 10 775
QRQ58661.1 0.0 2 783 3 783
SCV06580.1 0.0 2 783 3 783
QUT25652.1 0.0 2 783 3 783

PDB Hits      download full data without filtering help

Created with Snap3978118157196236275314354393432472511550590629668708747267695T9A_A277786B6L_A277787RSK_A297775T98_A297747CWD_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5T9A_A 2.95e-168 26 769 26 830
Crystalstructure of BuGH2Cwt [Bacteroides uniformis],5T9A_B Crystal structure of BuGH2Cwt [Bacteroides uniformis],5T9A_C Crystal structure of BuGH2Cwt [Bacteroides uniformis],5T9A_D Crystal structure of BuGH2Cwt [Bacteroides uniformis],5T9G_A Crystal structure of BuGH2Cwt in complex with Galactoisofagomine [Bacteroides uniformis],5T9G_B Crystal structure of BuGH2Cwt in complex with Galactoisofagomine [Bacteroides uniformis],5T9G_C Crystal structure of BuGH2Cwt in complex with Galactoisofagomine [Bacteroides uniformis],5T9G_D Crystal structure of BuGH2Cwt in complex with Galactoisofagomine [Bacteroides uniformis]
6B6L_A 5.15e-166 27 778 7 769
Thecrystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838],6B6L_B The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838]
7RSK_A 5.63e-166 27 778 7 769
ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7RSK_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
5T98_A 2.91e-154 29 777 29 813
Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]
7CWD_A 3.70e-153 29 774 5 791
ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]

Swiss-Prot Hits      download full data without filtering help

Created with Snap397811815719623627531435439343247251155059062966870874725774sp|A7LXS9|BGH2A_BACO118770sp|T2KM09|PLH16_FORAG29774sp|T2KN75|PLH17_FORAG29764sp|P77989|BGAL_THEP33671sp|T2KPJ7|PLH8_FORAG
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A7LXS9 7.56e-180 25 774 42 838
Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09 2.46e-114 18 770 39 809
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KN75 1.57e-76 29 774 30 785
Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
P77989 1.06e-70 29 764 7 717
Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KPJ7 1.13e-54 3 671 28 717
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000269 0.998985 0.000163 0.000207 0.000171 0.000155

TMHMM  Annotations      download full data without filtering help

start end
5 22