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CAZyme Information: MGYG000001325_00550
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Fusobacterium_C gonidiaformans | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae; Fusobacterium_C; Fusobacterium_C gonidiaformans | |||||||||||
| CAZyme ID | MGYG000001325_00550 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipopolysaccharide core heptosyltransferase RfaQ | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 218280; End: 219287 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 71 | 312 | 3e-50 | 0.9688888888888889 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG0859 | RfaF | 4.28e-69 | 1 | 327 | 2 | 326 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| cd03789 | GT9_LPS_heptosyltransferase | 8.00e-67 | 2 | 327 | 1 | 275 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| pfam01075 | Glyco_transf_9 | 2.41e-26 | 72 | 299 | 4 | 236 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| TIGR02195 | heptsyl_trn_II | 1.56e-25 | 2 | 329 | 1 | 331 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK10422 | PRK10422 | 3.82e-25 | 2 | 289 | 7 | 306 | lipopolysaccharide core biosynthesis protein; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AVQ16255.1 | 8.23e-247 | 1 | 335 | 1 | 335 |
| AYZ73488.1 | 1.34e-193 | 1 | 334 | 1 | 336 |
| AZW08514.1 | 1.34e-193 | 1 | 334 | 1 | 336 |
| AVQ20463.1 | 1.90e-193 | 1 | 334 | 1 | 336 |
| AYV92211.1 | 1.90e-193 | 1 | 334 | 1 | 336 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3TOV_A | 1.78e-13 | 2 | 293 | 10 | 309 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P25742 | 4.13e-15 | 12 | 287 | 5 | 292 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
| Q57336 | 2.61e-14 | 5 | 260 | 13 | 272 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
| Q9R9D5 | 4.53e-14 | 10 | 287 | 3 | 292 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| P37692 | 2.36e-12 | 1 | 281 | 1 | 296 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P45042 | 3.15e-12 | 1 | 329 | 1 | 342 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.998296 | 0.001628 | 0.000109 | 0.000004 | 0.000002 | 0.000008 |