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CAZyme Information: MGYG000001332_00835

You are here: Home > Sequence: MGYG000001332_00835

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Massilioclostridium methylpentosum
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Massilioclostridium; Massilioclostridium methylpentosum
CAZyme ID MGYG000001332_00835
CAZy Family GT28
CAZyme Description UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
371 MGYG000001332_11|CGC2 40428.16 9.6412
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001332 3406391 Isolate not provided not provided
Gene Location Start: 970460;  End: 971575  Strand: -

Full Sequence      Download help

MKVLLAAGGT  AGHINPAIAI  ADAIKAHQPD  AEILFAGTPN  GMEAKLVPKA  GYAFRPIKVR60
GFQRKLTPQN  IIKNIEAVKC  LVTSNFVADK  ILKDFQPDLV  IGTGGYASGP  VVQKAAKRGI120
KTAIHEQNAY  PGITNKMLSK  QVDLVMLAVE  EAKKMFPQNA  KIVVTGNPIR  SSILKKSKEE180
ARRELGMDDE  LCILSFGGSL  GAVKVNEIAA  DLIQWHYKKG  NVNHIHACGR  LGKDLFPQML240
KERGVDLTGC  PRIDVREYIH  DMDTCLAAAD  LVVCRAGAIT  LSELEATGKA  SILIPSPHVA300
ENHQYHNAMV  LQNHNAAIVI  EEKNYSKQKL  IATVNSLYTD  RKRLLTLSEN  AKSLAILDTA360
QRIYTALMNI  L371

Enzyme Prediction      help

No EC number prediction in MGYG000001332_00835.

CAZyme Signature Domains help

Created with Snap1837557492111129148166185204222241259278296315333352193356GT28
Family Start End Evalue family coverage
GT28 193 356 7e-47 0.9681528662420382

CDD Domains      download full data without filtering help

Created with Snap18375574921111291481661852042222412592782963153333522364GT28_MurG1371murG1367MurG1367murG193363Glyco_tran_28_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03785 GT28_MurG 1.52e-122 2 364 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
PRK00726 murG 1.44e-120 1 371 2 355
undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional
COG0707 MurG 2.75e-94 1 367 1 351
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].
TIGR01133 murG 8.31e-91 1 367 1 348
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
pfam04101 Glyco_tran_28_C 6.35e-35 193 363 2 166
Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.

CAZyme Hits      help

Created with Snap18375574921111291481661852042222412592782963153333521368BCI60898.1|GT281370CBL17600.1|GT281371QEY33586.1|GT281371QAT50143.1|GT281371CAB1239505.1|GT28
Hit ID E-Value Query Start Query End Hit Start Hit End
BCI60898.1 1.53e-142 1 368 1 368
CBL17600.1 6.66e-141 1 370 1 370
QEY33586.1 3.35e-136 1 371 1 370
QAT50143.1 4.28e-135 1 371 1 370
CAB1239505.1 1.61e-132 1 371 1 370

PDB Hits      download full data without filtering help

Created with Snap183755749211112914816618520422224125927829631533335223703S2U_A23631F0K_A33467D1I_A832934WYI_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
3S2U_A 2.24e-46 2 370 4 354
Crystalstructure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex [Pseudomonas aeruginosa PAO1]
1F0K_A 1.64e-45 2 363 8 346
The1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1F0K_B The 1.9 Angstrom Crystal Structure Of E. Coli Murg [Escherichia coli],1NLM_A Crystal Structure Of Murg:glcnac Complex [Escherichia coli],1NLM_B Crystal Structure Of Murg:glcnac Complex [Escherichia coli]
7D1I_A 3.60e-43 3 346 12 340
ChainA, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_B Chain B, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii],7D1I_C Chain C, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Acinetobacter baumannii]
4WYI_A 1.43e-09 83 293 91 312
Thecrystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form) [Arabidopsis thaliana],4X1T_A The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP [Arabidopsis thaliana]

Swiss-Prot Hits      download full data without filtering help

Created with Snap18375574921111291481661852042222412592782963153333521371sp|A3DE27|MURG_ACET21371sp|B8I6H3|MURG_RUMCH1370sp|B0K3H0|MURG_THEPX1370sp|B0K8K7|MURG_THEP31354sp|B1I4C4|MURG_DESAP
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DE27 4.44e-106 1 371 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=murG PE=3 SV=1
B8I6H3 1.01e-92 1 371 1 364
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=murG PE=3 SV=1
B0K3H0 2.58e-90 1 370 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter sp. (strain X514) OX=399726 GN=murG PE=3 SV=1
B0K8K7 2.58e-90 1 370 1 363
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=murG PE=3 SV=1
B1I4C4 3.07e-88 1 354 1 351
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase OS=Desulforudis audaxviator (strain MP104C) OX=477974 GN=murG PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000052 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001332_00835.