CAZyme Information: MGYG000001338_00511

Basic Information

• Species: Blautia_A wexlerae_A
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A wexlerae_A
• CAZyme ID: MGYG000001338_00511
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
816	MGYG000001338_1|CGC10	96381.91	5.2388

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000001338	3930699	Isolate	not provided	not provided

• Gene Location: Start: 555055; End: 557505 Strand: -

Full Sequence      

MEKIKLNENWRMRCLNNGRISSEWQNAVVPGSVYTDLLRNHQIQDPYWKDNEDSVCALME
EEYEYECTFMNYGTDGYTDIYLEFEGLDTVADIYLNDGYVGHAENMHRIWKYDVKSILRK
GENQLRIIFRSPLKYIAEAYKKYGNIGNDDTFEGFMHLRKAHYMFGWDWGAHLPDAGIFR
PVWLCKETGGRIESVYICQNHEEGRCTLEFKGEYVLTQPGNYRTLVTLKSPCGEIMETEL
DADGDGRIVIDHPLLWWVNGLGEQPLYEVEAVLMLEEKTVDTWKRRIGLRSMTVRREKDE
WGESFAHEINGVAFFAMGGDYIPEEHLLGRRSEEKTRQLLLDCKRANFNVIRVWGGGFYP
DEWFYDICDELGLAVWQDFMFACSVYELTEAFETNIRQEFIDNIKRLRHHPSLALWCGNN
EMEMFVDERCWVTKHTEVRDYLLMYERIIPEILKDHDHQTFYWPASPSSGGSFDEPNDPA
RGDVHYWKVWHGNRPFPEYRKFFFRYLSEFGFQSFPCKKTIDTFTDDPADWNIFSYVMEK
HQRNYGANGKIMNYMQQMYRYPGDFETVLYASQLLQADAIRYGVEHFRRNRGRCMGAVYW
QINDCWPVISWSSIDYCGRWKALHYYAKRFFAPVMISCEEESWMTAEANMNRQHFVFPKS
IRLHVANETMETRKILVKWQIRNAKAQILREEENIVVVSPMSGQWLEKVKLPEINVFCEY
VSYEAWEAGEKISEGTTIFSYPKYFRYEDPKLSFSINNDEITVTANAYAKSVEIQNENQD
LVLSDNYFDLNSNSRTVKILRGNSTGIRVRSVYQIR

Enzyme Prediction     

No EC number prediction in MGYG000001338_00511.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	2	763	1.2e-97	0.7566489361702128

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	9.82e-90	1	642	10	640	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340	ebgA	1.48e-11	6	421	44	449	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam17753	Ig_mannosidase	3.59e-10	749	813	1	77	Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.
pfam00703	Glyco_hydro_2	4.43e-07	191	290	2	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam17786	Mannosidase_ig	5.51e-07	661	744	3	91	Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AWY97345.1	0.0	1	816	1	811
ANU78706.2	0.0	10	816	40	849
ASU31771.1	0.0	10	816	40	849
QBE96379.1	0.0	2	816	24	841
QQQ95478.1	0.0	21	816	6	808

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
2VJX_A	2.08e-148	21	790	22	806	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A	2.19e-148	21	790	24	808	Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A	2.25e-148	21	790	24	808	ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A	5.93e-148	21	790	22	806	Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
2VQU_A	2.45e-146	21	790	22	806	Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQU_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q4WAH4	1.37e-113	1	790	4	818	Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1
B0YBU9	2.68e-113	1	790	4	818	Beta-mannosidase B OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OX=451804 GN=mndB PE=3 SV=1
A1D911	1.43e-112	1	790	4	818	Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mndB PE=3 SV=1
A1CGA8	5.46e-112	1	790	4	818	Beta-mannosidase B OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=mndB PE=3 SV=1
Q0CCA0	9.00e-106	27	696	30	719	Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000058	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000001338_00511.